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The Bone-Biomaterial Interface for Load-Bearing Implants

Published online by Cambridge University Press:  29 November 2013

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Extract

Bone-interfacing surgical implants used in orthopedics and dentistry must bear the forces of normal patient activity with minimal risk of mechanical failure of the implant. This requires using appropriate materials and designs for implant fabrication. Additionally, reliable long-term implant attachment to host bone must be assured so that effective force transfer between implant and bone occurs for the patient's lifetime without the implant loosening. With recent advances in implant designs and techniques for their placement, effective implant fixation to bone can last for years (decades) either directly or through an acceptable intermediate fibrous tissue layer at the bone-implant interface. With approximately 500,000 artificial hips implanted annually worldwide and the demand for other joint replacements approaching the same order of magnitude, as well as the recent major growth in the use of dental implants (300,300 projected for insertion in North America alone in 1991), the assurance of effective implant-to-bone fixation is extremely important.

Studies of implant biocompatibility have resulted from concerns over the cumulative effects of foreign element release through implant corrosion and wear. Accumulation of this debris in tissues both local and remote to implant sites over the long term is a concern. Of equal importance, for load-bearing implants, are studies to determine the important factors for successful long-term implant fixation. Current trends in design and use of both dental and orthopedic implants reflect the trial-and-error approach that has characterized this field for decades.

Type
Biomedical Materials
Copyright
Copyright © Materials Research Society 1991

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References

1.Adell, R., Lekholm, U., Rockler, B., and Branemark, P-I., Int. J. Oral Surg. 10 (1981) p. 387.CrossRefGoogle Scholar
2.Linder, L., in Biocompatibility of Orthopedic Implants, edited by Williams, D.F. (CRC Press, Boca Raton, FL, 1982) Vol. II, p. 1.Google Scholar
3.Pilliar, R.M., Clin. Orthop. 176 (1983) p. 42.CrossRefGoogle Scholar
4.Geesink, R.G.T., de Groot, K., and Klein, C.PA., Clin. Orthop. 225 (1987) p. 147.CrossRefGoogle Scholar
5.Williams, D.F., in Biocompatibility of Orthopaedic Implants, edited by Williams, D.F. (CRC Press, Boca Raton, FL 1982) Vol. I, p. 1.Google Scholar
6.Smith, G.K., in Systemic Aspects of Biocompatibility, edited by Williams, D.F. (CRC Press, Boca Raton, FL, 1981) Vol II, p. 1.Google Scholar
7.Woodman, J.L., Black, J., and Jiminez, S.A., J. Biomed. Mater. Res. 18 (1984) p. 99.CrossRefGoogle Scholar
8.Davies, J.E., in Handbook of Bioactive Ceramics, edited by Yamamuro, T., Hench, L.L., and Wilson, J. (CRC Press, Boca Raton, FL, 1990) Vol. 1, p. 195.Google Scholar
9.Ogura, M., Sakae, T., and Davies, J.E., in Bioceramics, edited by Bonfield, W., Hastings, G.W., and Tanner, H.E. (Butterworth Heinemann, London, 1991) Vol. 4, in press.Google Scholar
10.Davies, J.E., Ottensmeyer, P., Shen, X., Hashimoto, M., and Peel, S.A.F., in The Bone-Biomaterial Interface, edited by Davies, J.E. (University of Toronto Press, Toronto, 1991) p. 214.CrossRefGoogle Scholar
11.Coombs, N.A., Weatherly, G.C., and Pilliar, R.M., in Biomedical Materials and Devices, edited by Hanker, J.S. and Giammara, B.L. (Mater. Res. Soc. Symp. Proc. 110, Pittsburgh, PA, 1987) p. 349.Google Scholar
12.Davies, J.E., Pilliar, R.M., Smith, D.C., and Chernecky, R., in Bioceramics, edited by Bonfield, W., Hastings, G.W., and Tanner, H.E. (Butterworth Heinemann, London, 1991) Vol. 4, in press.Google Scholar
13.Davies, J.E., Nagai, N., Takeshita, N., and Smith, D.C., in The Bone-Biomaterial Interface, edited by Davies, J.E. (University of Toronto Press, Toronto, 1991) p. 285.CrossRefGoogle Scholar
14.Pilliar, R.M. and Weatherly, G.C., CRC Critical Reviews in Biocompatibility (1986) Vol. 1, p. 373.Google Scholar
15.Spector, M., in Biocompatibility of Orthopaedic Implants, edited by Williams, D.F. (CRC Press, Boca Raton, FL, 1982) Vol. II, p. 89.Google Scholar
16.Spector, M., Biocompatibility of Orthopaedic Implants, edited by Williams, D.F. (CRC Press, Boca Raton, FL, 1982) Vol. II, p. 55.Google Scholar
17.Williams, D.F., Biocompatibility of Orthopaedic Implants, edited by Williams, D.F. (CRC Press, Boca Raton, FL, 1982) Vol. II, p. 49.Google Scholar
18.Thomas, K.A., Kay, J.F., Cook, S.D., and Jarcho, M., J. Biomed. Mater. Res. 21 (1987) p. 1395.CrossRefGoogle Scholar
19.Block, M.S., Kent, J.N., and Kay, J.E, J. Oral Maxillofac. Surg. 45 (1987) p. 601.CrossRefGoogle Scholar
20.Cook, S.D., Thomas, K.A., Kay, J.F., and Jarcho, M., Clin. Orthop. 232 (1988) p, 225.CrossRefGoogle Scholar
21.de Groot, K., Geesink, R.G.T., Klein, C.P.A.T., and Serekian, P., J. Biomed. Mater. Res. 21 (1987) p. 1375.CrossRefGoogle Scholar
22.Block, M.S., Guerra, L.R., Kent, J.N., and Finger, I.M., Int. J. Oral Maxillofac. Implants 2 (1987) p. 111.Google Scholar
23.Hench, L.L., in Bioceramics: Material Characteristics Versus In Vivo Behavior, edited by Ducheyne, P. and Lemons, J., (New York Academy of Sciences, New York, NY, 1988) p. 54.Google Scholar
24.Daculsi, G., LeGeros, R.Z., and Heuhebaert, M., Calc. Tiss. Int. 46 (1990) p. 20.CrossRefGoogle Scholar
25.Hench, L.L. and Clark, A.E., in Biocompatibility of Orthopedic Implants, edited by Williams, D.F. (CRC Press, Boca Raton FL, 1982) Vol. II, p. 129.Google Scholar
26.Kokubo, T., J. Non-Cryst. Solids 102 (1990) p. 138.CrossRefGoogle Scholar
27.Spivak, J.M., Ricci, J.L., Blumenthal, N.C., and Alexander, H., J. Biomed. Mater. Res. 24 (1990) p. 1121.CrossRefGoogle Scholar
28.Cook, S.D., Kay, J.F., Thomas, K.A., and Jarcho, M., Int. J. Oral Maxillofac. Implants 2 (1987) p. 15.Google Scholar
29.Filiaggi, M.J., Coombs, N.A., and Pillar, R.M., “Characterization of the Interface in the Plasma Sprayed HA Coating/Ti-6Al-4V Implant System,” J. Biomed. Mater. Res. (in press, 1991).Google ScholarPubMed
30.Gross, U. and Strunz, V., J. Biomed. Mater. Res. 19 (1985) p. 251.CrossRefGoogle Scholar
31.Albrektsson, T., Branemark, P-I., Hansson, H-A., Kasemo, B., Larsson, K., Lundstrom, I., McQueen, D.H., and Salak, R., Ann. Biomed. Eng. 11 (1983) p. 1.CrossRefGoogle Scholar
32.Davies, J.E., Lowenberg, B., and Shiga, A., J. Biomed. Mater. Res. 24 (1990) p. 1289.CrossRefGoogle Scholar
33.Kasemo, B. and Laussma, J., J. Oral Maxillofac. Implants 3 (1988) p. 247.Google Scholar
34.Hanawa, T., in The Bone-Biomaterial Interface, edited by Davies, J.E. (University of Toronto Press, Toronto, 1991) p. 49.Google Scholar
35.Mears, D.C., J. Bone Jt. Surg. 45B (1976) p. 567.Google Scholar
36.Gruen, T.A.,Gregory, M.S., McNeice, G.M., and Amstustz, H.C., Clin. Orthop. 141 (1979) p. 17.Google Scholar
37.Bobyn, J.D., Pilliar, R.M., Cameron, H.U., and Weatherly, G.C., Clin. Orthop. 150 (1980) p. 263.CrossRefGoogle Scholar
38.Bobyn, J.D., Engh, C.A., and Glassman, A.H., Clin. Orthop. 224 (1987) p. 303.CrossRefGoogle Scholar
39.Davies, J.E., Chernecky, R., Lowenberg, B., and Shiga, A., Cells & Materials 1 (1) (1991) p. 3.Google Scholar
40.Lowenberg, B., Chernecky, R., Shiga, A., and Davies, J.E., Cells & Materials 1 (2) (1991) in press.Google Scholar
41.Pilliar, R.M., J. Biomed. Mater. Res: Appl. Biomat. 21 (A1) (1987) p. 1.CrossRefGoogle Scholar
42.Sodhi, R.N.S., Weninger, A., Davies, J.E., and Sreenivas, K., JAVS (1991), in press.Google Scholar
43.Maniatopoulos, C., Sodek, J., and Melcher, A.H., Cell Tiss. Res. 254 (1988) p. 317.CrossRefGoogle Scholar
44.Smith, D.C., Pilliar, R.M., and Mclntyre, N.S., in Oral Implantology and Biomaterials, edited by Kawahara, H. (Elsevier, Amsterdam, 1989) p. 185.Google Scholar
45.Smith, D.C., in The Bone-Biomaterial Interface, edited by Davies, J.E. (University of Toronto Press, Toronto 1991) p. 3.Google Scholar
46.Asmussen, E. and Munksgaard, E.C., in Posterior Composite Resin Dental Restorative Materials, edited by Vanherle, G. and Smith, D.C., (Peter Szulc, The Netherlands, 1985) p. 217.Google Scholar
47.Bobyn, J.D., Pilliar, R.M., Cameron, H.U., Weatherly, G.C., and Kent, G.M., Clin. Orthop. 149 (1980) p. 291.CrossRefGoogle Scholar
48.Pilliar, R.M., Deporter, D.A., Watson, P.A., Pharoah, M., Chipman, M., Valiquette, N., Carter, S., and de Groot, K., J. Dent. Res. (accepted 1991).Google Scholar
49.Williams, D.F., in Biocompatibility of Orthopedic Implants (CRC Press, Boca Raton, FL, 1982) Vol. I, p. 231.Google Scholar
50.Pilliar, R.M., Cameron, H.U., Welsh, R.P., and Binnington, A.G., Clin. Orthop. 156 (1981) p. 249.CrossRefGoogle Scholar
51.Ducheyne, P., Hench, L.L., Kagan, A., Martens, M., Bursens, A., and Mulier, J.C., J. Biomed. Mater. Res. 14 (1980) p. 225.CrossRefGoogle Scholar
52.Rivero, D.P., Fox, J., Skipor, A.K., Urban, R.M., and Galante, J.O., J. Biomed. Mater. Res. 22 (1988) p. 191.CrossRefGoogle Scholar