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Multiple regression analysis of As ground-water hazard and assessment of As-attributable human health risks in Chakdha Block,West Bengal

  • D. Mondal (a1), A. Hegan (a1) (a2), L. Rodriguez-Lado (a2), M. Banerjee (a3), A. K. Giri (a3) and D. A. Polya (a1)...

Extract

Soluble inorganic As is toxic with both cancer and non-cancer endpoints. Of the 80 million people in West Bengal, 50 million are living in the nine As-affected districts with millions at risk from using water for drinking, cooking or irrigation (Chakraborti et al., 2004). An environmental tragedy is developing in West Bengal with an alarming number of cases of skin lesions (Guha Mazumder et al., 1998; Mukherjee et al., 2005), respiratory symptoms (von Ehrenstein et al., 2005), adverse pregnancy outcomes and infant mortality (von Ehrenstein et al., 2006) and neurological complications (Mukherjee et al., 2005) associated with ingestion of As-contaminated water.

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Banerjee, M., Sarkar, L. Das, J.K., Mukherjee, A., Sarkar, A.K., Mondal, L. and Giri, A.K. (2007) Polymorphism in the ERCC2 codon 751 is associated with arsenic-induced premalignant hyper-keratosis and significant chromosome aberrations. Carcinogenesis, 28, 672–676.
Basu, A., Mahata, I. Gupta, S. and Giri, A.K. (2001) Genetic toxicology of a paradoxical human carcinogen, arsenic: a review. Mutation Research, 488, 171–194.
Chakraborti, D., Sengupta, M.K., Rahman, M.M., Ahamed, S., Chowdhury, U.K., Hossain, M.A., Mukherjee, S.C., Pati, S., Sana, K.C., Dutta, R.N. and Quamruzzaman, Q. (2004) Groundwater arsenic contamination and its health effects in the Ganga-Meghna-Brahmaputra plain. Journal of Environmental Monitoring, 6, 74N—83N.
de Chaudhuri, S., Mahata, J., Das, J.K., Mukherjee, A., Ghosh, P., Sau, T.J., Mondal, L., Basu, S., Giri, A.K. and Roychoudhury, S. (2006) Association of specific p53 polymorphisms with keratosis in individuals exposed to arsenic through drinking water in West Bengal, India. Mutagen Research, 601, 102–112.
de Chaudhuri, S., Ghosh, P., Sarma, N., Majumdar, P., Sau, T.J., Basu, S., Roychoudhury, S., Ray, K. and Giri, A.K. (2008) Genetic variants associated with arsenic susceptibility: study of purine nucleoside phosphorylase, arsenic (+3) methyl transferase and glutathione S-transferase omega genes. Environmental Health Perspectives, 116, 501–505.
Fewtrell, L., Fuge, F. and Kay, D. (2005) Estimation of the global burden of disease due to skin lesions caused by arsenic in drinking water. Journal of Water and Health, 3.2, 101–107.
Guha Mazumder, D.N., Haque, R., Ghosh, N., de, B.K, Santra, A., Chakraborty, D. and Smith, A.H. (1998) Arsenic levels in drinking water and the prevalence of skin lesions in West Bengal, India. International Journal of Epidemiology, 27, 871–877.
Lokuge, K.M., Smith, W., Caldwell, B., Dear, K and Milton, A. (2004) The effect of arsenic mitigation interventions on disease burden in Bangladesh. Environmental Health Perspectives, 112, 1172–1177.
Mondal, D. and Polya, D.A. (2008) Rice is a major exposure route for arsenic in Chakdha Block, West Bengal: a Probabilistic Risk Assessment. Applied Geochemistr. (in press).
Mondal, D., Adamson, G.C.D., Nickson, R. and Polya, D.A. (2008) A comparison of two techniques for calculating groundwater arsenic-related lung, bladder and liver cancer disease burden using data from Chakdha Block, West Bengal. Applied Geochemistr. (in press).
Mukherjee, S.C., Sana, K.C., Pati, S., Dutta, R.N., Rahman, M.M., Sengupta, M.K, Ahamed, S., Lodh, D., Das, B., Hossain, M.A., Nayak, B., Mukherjee, A., Chakraborti, D., Dulta, S.K, Palit, S.K., Kaies, I., Barua, A.K. and Asad, K.A. (2005) Murshidabad -One of the nine groundwater arsenic-affected districts of West Bengal, India. Part II: Dermatological, neurological, and obstetric findings. Clinical Toxicology, 43, 835–848.
Murray, CJ. and Lopez, A.D. (editors) (1996) The Global Burden of Disease: A Comprehensive Assessment of Mortality and Disability from Diseases, Injuries, and Risk Factors in 1990 and Projected to 2020. Global Burden of Disease and Injury, Vol. 1. Harvard School of Public Health, Cambridge, Massachusetts, USA.
NRC (1999) Arsenic in Drinking Water. National Academy Press, Washington, D.C.
Paustenbach, DJ. (2000) The practice of exposure assessment: A state-of-the-art review (Reprinted from Principles and Methods of Toxicology, 4th edition, 2001). Journal of Toxicology and Environmental Health-Part B—Critical Reviews, 3, 179–291.
Rodriguez-Lado, L., Polya, D.A., Winkel, L., Berg, M. and Hegan, A. (2008) Modelling arsenic hazard in groundwater in Cambodia: a geostatistical approach using ancillary data. Applied Geochemistry, (in press).
Smith, A.H., Hopenhayn-Rich, C, Bates, M.N., Goeden, H.M., Hertz-Picciotto, I., Duggan, H.M., Wood, R., Kosnett, MJ. and Smith, M.T. (1992) Cancer Risks from Arsenic in Drinking-Water. Environmental Health Perspectives, 97, 259–267.
Vahter, M. (1999) Methylation of inorganic arsenic in different mammalian species and population groups. Science Progress, 82, 69–88.
von Ehrenstein, O.S., Mazumder, D.N., Yuan, Y., Samanta, S., Balmes, J., Sil, A., Ghosh, N., Hira-Smith, M., Haque, R., Purushothamam, R., Lahiri, S., Das, S. and Smith, A.H. (2005) Decrements in lung function related to arsenic in drinking water in West Bengal, India. American Journal of Epidemiology, 162, 533–541.
von Ehrenstein, O.S., Guha Mazumder, D.N., Hira-Smith, M., Ghosh, N., Yuan, Y., Windham, G., Ghosh, A., Haque, R., Lahiri, S., Kalman, D., Das, S. and Smith, A.H. (2006) Pregnancy outcomes, infant mortality, and arsenic in drinking water in West Bengal, India. American Journal of Epidemiology, 163, 662–669.
WHO (2001) Environmental Health Criteria 224. Arsenic and Arsenic Compounds. World Health Organization, Geneva.
Yu, W.H., Harvey, CM. and Harvey, C.F. (2003) Arsenic in groundwater in Bangladesh: A geostatistical and epidemiologieal framework for evaluating health effects and potential remedies. Water Resources Research, 39, 1146–1151.

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