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Severed Actin and Microtubules with Motors Walking All Over Them: Cryo-EM Studies of Seriously Perturbed Helical Assemblies

Published online by Cambridge University Press:  05 August 2019

Garrett Debs ,
Andrew Huehn ,
Michael Cha ,
Xueqi Liu ,
William A. Elam ,
Wenxiang Cao ,
Enrique De La Cruz  and
Charles V. Sindelar
Garrett Debs
Affiliation:
Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT, USA.
Andrew Huehn
Affiliation:
Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT, USA.
Michael Cha
Affiliation:
Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT, USA.
Xueqi Liu
Affiliation:
Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT, USA.
William A. Elam
Affiliation:
Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT, USA.
Wenxiang Cao
Affiliation:
Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT, USA.
Enrique De La Cruz
Affiliation:
Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT, USA.
Charles V. Sindelar*
Affiliation:
Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT, USA.
*
*Corresponding author: chuck.sindelar@yale.edu

Abstract

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Type
Cryo-EM - from Physics to Cell Biology: Honoring the Remarkable Legacy of Ken Downing
Information
Microscopy and Microanalysis , Volume 25 , Supplement S2 , August 2019 , pp. 1362 - 1363
Copyright
Copyright © Microscopy Society of America 2019 

Footnotes

2

Present address: C4 Therapeutics, Cambridge, MA, USA.

References

[1]Huehn, A. et al. , J Biol Chem 293 (2018), p. 5377.Google Scholar
[2]Bai, XC et al. , Elife, 2015. 4.Google Scholar
[3]De La Cruz, E, Biophysical Reviews 1 (2009), p. 51.Google Scholar
[4]Cao, L et al. , Nat Commun 5 (2014), p. 5364.Google Scholar
[5]Shang, Z et al. , Elife, 3 (2014), p. e04686.Google Scholar