Hostname: page-component-77c89778f8-cnmwb Total loading time: 0 Render date: 2024-07-20T23:03:14.987Z Has data issue: false hasContentIssue false
  • English
  • Français

Optimizing Throughput for Cryo-EM Data Collection in Drug Discovery

Published online by Cambridge University Press:  30 July 2021

Stephen Mick ,
Sahil Gulati  and
Christopher Booth
Stephen Mick
Affiliation:
Gatan, United States
Sahil Gulati
Affiliation:
Gatan, United States
Christopher Booth
Affiliation:
Gatan, United States

Abstract

An abstract is not available for this content so a preview has been provided. As you have access to this content, a full PDF is available via the ‘Save PDF’ action button.
Image of the first page of this content. For PDF version, please use the ‘Save PDF’ preceeding this image.'
Type
Imaging, Microscopy, and Micro/Nano-Analysis of Pharmaceutical, Biopharmaceutical, and Medical Health Products
Information
Microscopy and Microanalysis , Volume 27 , Supplement S1 , August 2021 , pp. 288 - 289
Check for updates
Copyright
Copyright © The Author(s), 2021. Published by Cambridge University Press on behalf of the Microscopy Society of America

References

Kühlbrandt, W., (2014), The Resolution Revolution, Science, 343 (6178), 1443-1444, doi:10.1126/science.1251652.CrossRefGoogle ScholarPubMed
Hanske, J., Sadian, Y., Müller, C.W., (2018), The cryo-EM resolution revolution and transcription complexes, Current Opinions in Structural Biology, 52:8-15, doi.org/10.1016/j.sbi.2018.07.002.CrossRefGoogle ScholarPubMed
de Oliveira, Maia, van Beek, T., Shilliday, L., Debreczeni, F., Phillips, J.E., C., (2020), Cryo-EM: The Resolution Revolution and Drug Discovery, SLAS Discovery: Advancing the Science of Drug Discovery, 26(10), 17-31, doi.org/10.1177/2472555220960401.CrossRefGoogle ScholarPubMed
Weis, F., Hagen, W., (2020), Combining high throughput and high quality for cryo-electron microscopy data collection, Acta Crystallographica Section D: Structural Biology, 76(8), 724-728, doi.org/10.1107/S2059798320008347.CrossRefGoogle ScholarPubMed