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Focal Adhesion Kinase Anchoring Kinetics and Regulatory Interactions Quantified by Total Internal Reflection Fluorescence Microscopy

Published online by Cambridge University Press:  23 September 2015

Taylor Zak ,
Allen M. Samarel  and
Seth L. Robia
Taylor Zak
Affiliation:
Department of Cell and Molecular Physiology, Stritch School of Medicine, Loyola University Chicago, Maywood, ILUSA
Allen M. Samarel
Affiliation:
Department of Cell and Molecular Physiology, Stritch School of Medicine, Loyola University Chicago, Maywood, ILUSA Department of Medicine, Stritch School of Medicine, Loyola University Chicago, Maywood, ILUSA
Seth L. Robia
Affiliation:
Department of Cell and Molecular Physiology, Stritch School of Medicine, Loyola University Chicago, Maywood, ILUSA

Abstract

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Type
Abstract
Information
Microscopy and Microanalysis , Volume 21 , Supplement S3: Proceedings of Microscopy & Microanalysis 2015 , August 2015 , pp. 69 - 70
Copyright
Copyright © Microscopy Society of America 2015 

References

[1] Koshman, YE, Engman, SJ, Kim, T, Iyengar, R, Henderson, KK & Samarel, AM. Role of FRNK tyrosine phosphorylation in vascular smooth muscle spreading and migration. Cardiovasc Res. 2010;85:571–581.CrossRefGoogle ScholarPubMed
[2] Brami-Cherrier, K, Gervasi, N, Arsenieva, D, Walkiewicz, K, Boutterin, MC, Ortega, A, et al. FAK dimerization controls its kinase-dependent functions at focal adhesions. EMBO J. 2014;33:356–370.Google Scholar
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[4] Goni, GM, Epifano, C, Boskovic, J, Camacho-Artacho, M, Zhou, J, Bronowska, A, et al. Phosphatidylinositol 4,5-bisphosphate triggers activation of focal adhesion kinase by inducing clustering and conformational changes. Proc Natl Acad Sci U S A. 2014;111:E3177–86.Google Scholar
[5] The authors acknowledge funding from NIH (HL092321, HL062426).Google Scholar