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Advances in Cryo-EM structure-based methods in membrane protein drug discovery

Published online by Cambridge University Press:  30 July 2021

Michael Hennig*
Affiliation:
leadXpro AG, United States

Abstract

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Type
Cryo-EM in Drug Discovery
Copyright
Copyright © The Author(s), 2021. Published by Cambridge University Press on behalf of the Microscopy Society of America

References

Botte, Mathieu, Ulrich, Alexander K. C., Adaixo, Ricardo, Gnutt, David, Brockmann, Andreas, Bucher, Denis, Chami, Mohamed, Bocquet, Nicolas, Ebbinghaus-Kintscher, Ulrich, Puetter, Vera, Becker, Andreas, Egner, Ursula, Stahlberg, Henning, Hennig, Michael and Holton, Simon J., Cryo-EM structural studies of the agonist complexed human TRPV4 ion-channel reveals novel structural rearrangements resulting in an open-conformation (2020), https://doi.org/10.1101/2020.10.13.334797Google Scholar
Botte, Mathieu, Ni, Dongchun, Schenck, Stephan, Zimmermann, Iwan, Chami, Mohamed, Bocquet, Nicolas, Egloff, Pascal, Bucher, Denis, Trabuco, Matilde, Cheng, Robert K.Y., Brunner, Janine, Seeger, Markus A., Stahlberg, Henning and Hennig, Michael Insight into the lipopolysaccharide translocation by cryo-EM structures of a LptDE transporter in complex with Pro-Macrobodies. Manuscript submitted (2021)Google Scholar
Botte, Mathieu, Huber, Sophie, Bucher, Denis, Rodriges, David, Tagmose, Lena, Chami, Mohamed, Bocquet, Nicolas, Michael Hennig and Wassim Abdul Rahman. Manuscript in preparation (2021).Google Scholar