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Epidemiological Models and Lyapunov Functions

Published online by Cambridge University Press:  15 June 2008

A. Fall
Affiliation:
INRIA Lorraine & Université Paul Verlaine, Metz LMAM (UMR CNRS 7122) I.S.G.M.P. Bât A, Ile du Saulcy, 57045 Metz Cedex 01, France Université de Saint-Louis, Sénégal
A. Iggidr
Affiliation:
INRIA Lorraine & Université Paul Verlaine, Metz LMAM (UMR CNRS 7122) I.S.G.M.P. Bât A, Ile du Saulcy, 57045 Metz Cedex 01, France
G. Sallet*
Affiliation:
INRIA Lorraine & Université Paul Verlaine, Metz LMAM (UMR CNRS 7122) I.S.G.M.P. Bât A, Ile du Saulcy, 57045 Metz Cedex 01, France
J. J. Tewa
Affiliation:
INRIA Lorraine & Université Paul Verlaine, Metz LMAM (UMR CNRS 7122) I.S.G.M.P. Bât A, Ile du Saulcy, 57045 Metz Cedex 01, France Université de Yaoundé, Cameroun
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Abstract

We give a survey of results on global stability for deterministic compartmental epidemiological models. Using Lyapunov techniques we revisit a classical result, and give a simple proof. By the same methods we also give a new result on differential susceptibility and infectivity models with mass action and an arbitrary number of compartments. These models encompass the so-called differential infectivity and staged progression models. In the two cases we prove that if the basic reproduction ratio $\mathcal{R}_0$ 1, then the disease free equilibrium is globally asymptotically stable. If $\mathcal{R}_0$ > 1, there exists an unique endemic equilibrium which is asymptotically stable on the positive orthant.

Type
Research Article
Copyright
© EDP Sciences, 2007

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