In an earlier preliminary design study, we proposed a novel nuclear-pumped laser-driven (NPL) inertial confinement fusion (ICF) power reactor that represents an important variation on the “neutron feedback” concept for ICF. This NPL-driven ICF concept also included an advanced, DT-seeded, D3He-fueled pellet and magnetic protection of the first wall of the reactor chamber. Advantages that were demonstrated for this approach included increased efficiency for laser-to-target energy coupling, increased efficiency for thermalto-electric energy conversion, and reduced neutron activation and waste. The coupling efficiency is enhanced because a nuclear-pumped flashlamp is directly pumped by fission fragments from uranium micropellets within the lamp medium. The thermal conversion efficiency is greater because a large fraction of the ICF pellet&s fusion yield is in charged Finally, the fraction of the fusion yield carried by neutrons is significantly reduced in comparison with pure D-T-fueled pellets; thus, neutron-induced activity in the first wall is decreased and safety is increased. The initial study indicated these factors could result in a required driver energy of 5 MJ (vice 10 MJ currently projected) and a pellet gain of only 50 (vice 100 currently projected) for a feasible l,000-MWe power reactor operating with approximately six pellets per second. The current study includes a refined analysis of an NPL-driven ICF power reactor of this type. A cylindrical design for the fission/NPL blanket is selected as a “natural” geometry for pumping the NPL. Required enrichments and criticalities are then predicted for the multiplication of the fusion neutron yield needed to pump the NPL. Based upon these results, we report a more detailed parametric study of the efficiencies for converting neutron, X-ray, and plasma yields from advanced ICF pellets into electrical and optical energy flows required in this concept. We also examined breeding tritium in a lithium blanket layer. Results from these studies help define topics and parameter spaces for further research on this unique reactor concept.