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Radiation and thermal effects on polymeric immobilization devices used in patients submitted to radiotherapy

Published online by Cambridge University Press:  24 June 2011

C. Pereira-Loch ,
R. Benavides ,
M. Fogliato S. Lima  and
B.M. Huerta
C. Pereira-Loch
Affiliation:
Hospital Sao Jose (HSJ), Rua Cel. Pedro Benedet 630, 88801-250, Criciuma SC, Brasil
R. Benavides*
Affiliation:
Centro de Investigación en Química Aplicada, Blvd. Enrique Reyna 140, Saltillo, Coah., 25253, México
M. Fogliato S. Lima
Affiliation:
Universidade Luterana do Brasil, Av. Farroupilha 8001- PPGEAM, Prédio 29, S. 203, 92450-900, Canoas, RS, Brasil
B.M. Huerta
Affiliation:
Centro de Investigación en Química Aplicada, Blvd. Enrique Reyna 140, Saltillo, Coah., 25253, México
*
Correspondence to: R. Benavides, Centro de Investigación en Química Aplicada, Blvd. Enrique Reyna 140, Saltillo, Coah., 25253, México. E-mail: robertob@ciqa.mx
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Abstract

Immobilization devices in radiotherapy are made of a soft plastic easy to mould when immersed in hot water. Same item is usually used for 6 patients (according to protocol), but at Hospital Sao Jose (HSJ) they have been showing some deformation during the re-utilization process. The latter is the reason for this research where devices were treated with 6 thermal conditions, 6 irradiation procedures and the joint effect of both treatments. DSC, TGA and WAXD indicated devices are made of polycaprolactone (PCL), but no signs of degradation, except a slight variation in crystalinity; however, mechanical properties by means of Young’s modulus steadily increase its values through number of treatments up to a 20%. Activation energy (Ea) obtained by multi-ramps of TGA-Arrhenius evaluated for the most treated samples (6th treatment) indicates that temperature facilitates degradation while irradiation and joint treatments enhance the stability of PCL, apparently by crosslinking.

Keywords

Immobilization devicesradiotherapydegradationPCL
Type
Original Article
Information
Journal of Radiotherapy in Practice , Volume 11 , Issue 2 , June 2012 , pp. 101 - 106
Copyright
Copyright © Cambridge University Press 2012

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