Hostname: page-component-77c89778f8-fv566 Total loading time: 0 Render date: 2024-07-19T04:19:08.498Z Has data issue: false hasContentIssue false
  • English
  • Français

Dosimetric comparison of TMR10 and convolution dose calculation algorithms in GammaPlan treatment planning system

Published online by Cambridge University Press:  04 June 2019

Ethan Kendall ,
Ozer Algan ,
Yong Chen  and
Salahuddin Ahmad
Ethan Kendall*
Affiliation:
Department of Radiation Oncology, Peggy & Charles Stephenson Cancer Center, University of Oklahoma HSC, Oklahoma City, OK, USA
Ozer Algan
Affiliation:
Department of Radiation Oncology, Peggy & Charles Stephenson Cancer Center, University of Oklahoma HSC, Oklahoma City, OK, USA
Yong Chen
Affiliation:
Department of Radiation Oncology, Peggy & Charles Stephenson Cancer Center, University of Oklahoma HSC, Oklahoma City, OK, USA
Salahuddin Ahmad
Affiliation:
Department of Radiation Oncology, Peggy & Charles Stephenson Cancer Center, University of Oklahoma HSC, Oklahoma City, OK, USA
*
Author for correspondence: Ethan Kendall, Department of Radiation Oncology, Peggy & Charles Stephenson Cancer Center, University of Oklahoma HSC, 800 NE 10th St, Oklahoma City, OK 73104, USA. Tel: (405) 271-1112. E-mail: ethan-kendall@ouhsc.edu
Get access Rights & Permissions [Opens in a new window]

Abstract

Aims:

In this article, our goal is to compare the TMR10 and convolution dose calculation algorithm in GammaPlan used in stereotactic radiosurgery (SRS) treatments with Gamma Knife and to assess if the algorithms produce clinically significant differences.

Materials and methods:

Treatment plans were analysed from ten patients who have undergone Gamma Knife SRS treatments. Patient plans were retrospectively recalculated using Lesksell GammaPlan 10 treatment software utilising the TMR10 and convolution dose calculation algorithms in order to create a paired dataset for comparison. Evaluation was based on the dose volume histogram (parameters of minimum, mean, maximum and integral doses.

Results:

The ratios of average integral doses calculated by the convolution dose calculation algorithm to the average integral doses calculated by the TMR10 algorithm are 0·997 for the target (p=0·028), 1·048 (p=0·48) for the skull and 1·005 (p=0·68) for the brainstem.

Conclusions:

Although doses calculated with the convolution algorithm resulted in slightly higher mean integral doses for the brainstem and skull critical structures when compared to that of TMR10 doses, these results were not statistically or clinically significant. Thus we continue to use the TMR10 algorithm at our clinic.

Keywords

dosimetric comparisonGamma knifeheterogeneity correctionstereotactic radiosurgery
Type
Technical Note
Information
Journal of Radiotherapy in Practice , Volume 19 , Issue 1 , March 2020 , pp. 93 - 97
Check for updates
Copyright
© Cambridge University Press 2019 

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Kendall, E, Ahmad, S, Algan, O. Dosimetric comparison of sector-blocked and non-sector-blocked Gamma Knife Perfexion treatment plans for trigeminal neuralgia. Med Dosim 2018; 43 (4): 390–393.CrossRefGoogle ScholarPubMed
Elekta. A new TMR algorithm in Leksell GammaPlan White Paper. 2011. Stockholm, Sweden: Elekta.Google Scholar
Elekta. The convolution algorithm in Leksell GammaPlan White Paper. 2011. Stockholm, Sweden: Elekta.Google Scholar
Fallows, P, Wright, G, Harrold, N, Bownes, P. A comparison of the convolution and TMR10 treatment planning algorithms for Gamma Knife radiosurgery. J Radiosurg SBRT 2018; 5 (2): 157–167.Google Scholar
Nakazawa, H, Komori, M, Shibamoto, Y, Tsugawa, T, Mori, Y, Kobayashi, T. Dosimetric comparison of absolute and relative dose distributions between tissue maximum ratio and convolution algorithms for acoustic neurinoma plans in Gamma Knife radiosurgery. Acta Neurochir (Wien) 2014; 156 (8): 1483–1489.CrossRefGoogle ScholarPubMed
Osmancikova, P, Novotny, J, Solc, J, Pipek, J. Comparison of the convolution algorithm with TMR10 for Leksell Gamma knife and dosimetric verification with radiochromic gel dosimeter. J Appl Clin Med Phys 2018; 19 (1): 138–144.CrossRefGoogle ScholarPubMed
Rojas-villabona, A, Kitchen, N, Paddick, I. Investigation of dosimetric differences between the TMR 10 and convolution algorithm for Gamma Knife stereotactic radiosurgery. J Appl Clin Med Phys 2016; 17 (6): 217–229.CrossRefGoogle ScholarPubMed
Xu, A Y, Bhatnagar, J, Bednarz, G, et al. Gamma Knife radiosurgery with CT image-based dose calculation. J Appl Clin Med Phys 2015; 16 (6): 119–129.CrossRefGoogle ScholarPubMed