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Treatment of Anxiety States: II.—Clinical Trial of Benactyzine in Anxiety States

  • G. R. Hargreaves (a1), Max Hamilton (a1) and Julian M. Roberts (a1)

Extract

Of all the tranquillizers, it may well be said that benactyzine has had the most chequered history. After its synthesis, a series of most careful experiments on animals demonstrated its ability to reduce or modify behaviour induced by stress. The first clinical trial gave rise to high hopes of its value in treatment but as further trials, more carefully designed, were made the results became increasingly inconclusive.

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References

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Coady, A., and Jewesbury, E. C. O., “A clinical trial of benactyzine hydrochloride ('Suavitil') as a physical relaxant”, Brit. Med. J., 1956, i 485487.
Forbes, H. S., and Earle, B. V., “Benactyzine in psychoneurosis”, ibid., 1957, i, 226.
Glow, P., Personal communication, 1958.
Hamilton, M., “The rating of anxiety states”, 1958. In press.
Hargreaves, G. R., Hamilton, M., and Roberts, J. M., “Benactyzine as an aid in treatment of anxiety states”, Brit. Med. J., 1957, i 306310.
Jacobsen, N. E., Kehlet, J., Larsen, V., Munkvad, I., and Skinhoj, K., “Investigation into autonomic responses during emotion”, Acta Psychiat. Neurol. Scand., 1955, 30, 607625.

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Treatment of Anxiety States: II.—Clinical Trial of Benactyzine in Anxiety States

  • G. R. Hargreaves (a1), Max Hamilton (a1) and Julian M. Roberts (a1)
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