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Measurements of Effects of Hyaluronidase in Insulin Coma Treatment

Published online by Cambridge University Press:  08 February 2018

K. E. Schmidt  and
J. Tong
K. E. Schmidt
Affiliation:
Hill End Hospital, St. Albans, Herts
J. Tong
Affiliation:
Rampton Hospital, Retford, Notts
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Extract

Hyaluronidase, the “spreading factor” is widely used today to aid the distribution and absorption of fluids injected at various sites into body tissues. It is derived from the head of the male sperm cell which by its action dissolves hyaluronic acid in the “shell” surrounding the female egg cell and thereby allows spermal penetration and conception; generally speaking it dissolves the ground substance between cells. The most remarkable usage is in paediatrics where it allows for quick replacement of lost fluid and salt in gastro-enteritis, obviating the need to find veins, and thereby saving practically all cases from death by dehydration. There are many other uses.

Type
Original Articles
Information
Journal of Mental Science , Volume 104 , Issue 437 , October 1958 , pp. 1136 - 1148
Copyright
Copyright © Royal College of Psychiatrists, 1958 

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References

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