Hostname: page-component-77c89778f8-7drxs Total loading time: 0 Render date: 2024-07-23T11:02:44.675Z Has data issue: false hasContentIssue false

A Controlled Trial of Trifluoperazine in the Treatment of the Mentally Subnormal Patient

Published online by Cambridge University Press:  08 February 2018

D. S. Sharpe*
Affiliation:
Botleys Park Hospital. Chertsey, Surrey

Extract

The treatment of mentally subnormal patients is often complicated by abnormal behaviour, usually consisting of a mixture of aggression towards either themselves or others, extreme noisiness, hyperkinesis and general anti-social conduct. Because this presents great difficulties, particularly from the nursing point of view, the aim of all whose task it is to care for these patients has been to improve this behaviour pattern. However, until recently the treatment has been largely custodial, coupled with large and frequent doses of sedatives, usually of the barbiturate group. The advent of “tranquillizing” drugs, particularly the phenothiazines, seems to offer the possibility of controlling these disorders without reducing the patient to a vegetative state.

Type
Therapeutic Trials
Copyright
Copyright © Royal College of Psychiatrists, 1962 

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

1. Beaudry, P., and Gibson, D., “Effect of trifluoperazine in the behavioural disorders of children with malignant emotional disturbances”, Amer. J. ment. Defic., 1960, 64, 823826.Google Scholar
2. Claridge, G. S., “A re-analysis of excitability and its relationship with improvement in performance of imbeciles”, J. ment. Defic. Res., 1959, 3, 116121.Google Scholar
3. Claridge, G. S., and O'Connor, N., “The relationship between incentive, personality type and improvement in performance of imbeciles”, J. ment. Defic. Res., 1957, 1, 1625.Google Scholar
4. Lawlis, M. G., “A note on trifluoperazine in the management of hyperactive mentally retarded children.” In Trifluoperazine. Clinical and Pharmacological Aspects, Ed. Brill, H., 1958, pp. 181182. Phila: Lea and Febiger Google Scholar
5. LeVann, L. J., “The use of trifluoperazine as a tranquillizing agent in mentally defective children.” In Trifluoperazine. Further Clinical and Laboratory Studies, Ed. Brill, H. 1958, pp. 130135. Phila: Lea and Febiger.Google Scholar
6. Siegel, S., Nonparametric Statistics for the Behavioural Sciences, 1956. London: McGraw-Hill.Google Scholar
7. Terman, L. M., and Merrill, M. A., Measuring Intelligence. 1949. London: Harrap.Google Scholar
8. Vasconcellos, J., “Clinical evaluation of trifluoperazine in maximum-security braindamaged patients with severe behavioural disorders”, J. clin. exp. Psychopath, 1960, 21, 2530.Google Scholar
Submit a response

eLetters

No eLetters have been published for this article.