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In situ silver nanoparticle synthesis on 3D-printed polylactic acid scaffolds for biomedical applications

Published online by Cambridge University Press:  03 September 2020

Semih Calamak Open the ORCID record for Semih Calamak [Opens in a new window]  and
Menekse Ermis
Semih Calamak*
Affiliation:
Department of Basic Pharmaceutical Sciences, Faculty of Pharmacy, Hacettepe University, Ankara06100, Turkey
Menekse Ermis
Affiliation:
BIOMATEN, Middle East Technical University (METU) Center of Excellence in Biomaterials and Tissue Engineering, Ankara06800, Turkey
*
a)Address all correspondence to this author. e-mail: semihcalamak@hacettepe.edu.tr
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Abstract

An ultraviolet (UV) irradiation-based in situ silver nanoparticle (AgNP) synthesis approach has drawn significant attention for functionalizing a great variety of biomaterials. Here, we designed an AgNP-functionalized 3D-printed polylactic acid (PLA) composite scaffold with a green physical approach by employing the UV irradiation (1, 2, and 3 h) method without using any reducing agent or heat treatments. In situ AgNP synthesis was performed under different UV exposure times. The zeta sizer analysis results demonstrated that AgNPs were highly monodisperse with the particle size of 20 ± 2.2, 30 ± 3.6, and 50 ± 4.8 nm under various UV light exposure times. In situ synthesis of AgNPs on 3D-printed PLA scaffolds significantly changed the surface hydrophilicity of the 3D-printed scaffolds. These results showed that UV irradiation-based in situ AgNP synthesis on 3D-printed PLA scaffolds can be useful in various biomedical applications, such as cell culture scaffolds, biosensors, and wound healing applications.

Keywords

in situ3D printingscale-up/manufacturing
Type
Article
Information
Journal of Materials Research , First View , pp. 1 - 10
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Copyright
Copyright © Materials Research Society 2020

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