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Stapedotomy in osteogenesis imperfecta patients

  • E. Ferekidis, P. Stavroulaki, I. Vossinakis, J. Yiotakis, L. Manolopoulos and G. Adamopoulos...

Abstract

Osteogenesis imperfecta (OI) is a connective tissue disorder characterized by osseous fragility, blue sclerae and hearing loss. In order to assess the impact of stapedotomy on improving hearing on OI, a retrospective, one-group, pre-test-post-test design was used to compare the pre-operative and postoperative audiograms of nine OI patients, treated with stapedotomy for their mixed hearing loss. Operative findings included fixation or thickening of the stapes footplate with normal superstructure configuration and hypervascularization of the promontory mucosa. Immediate post-operative results showed a significant improvement (p<0.05) from 250–4000 Hz in air conduction and from 250–2000 Hz in bone conduction. A significant closure of the air-bone gap between 250–2000 Hz was also achieved (p<0.05). The long-term results remained satisfactory with a mean threshold shift of 8 dB HL and an almost unchanged air-bone gap. These satisfactory results and the lack of complications make stapedotomy an appealing method for the management of OI-associated hearing loss.

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Stapedotomy in osteogenesis imperfecta patients

  • E. Ferekidis, P. Stavroulaki, I. Vossinakis, J. Yiotakis, L. Manolopoulos and G. Adamopoulos...

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