Skip to main content Accessibility help
×
Home

A review of heterotopia and associated salivary gland neoplasms of the head and neck

  • Alfio Ferlito (a1), Giulia Bertino (a1), Alessandra Rinaldo (a1), Giacinto M. Mannarà (a2) and Kenneth O. Devaney (a3)...

Abstract

Salivary tissue neoplasms may involve normal, accessory and heterotopic salivary gland tissue. A case of Warthin's tumour originating from heterotopic salivary gland tissue of the upper neck is reported. The radioactive uptake of 131I, evidenced in the neck mass in its pre-diagnostic assessment, suggested a diagnosis of cervical node involvement from a primary malignant thyroid neoplasm. A critical review of the literature on heterotopic salivary gland tissue neoplasms of the head and neck is also presented.

Copyright

Corresponding author

Address for correspondence: Alfio Ferlito, M.D., Department of Otolaryngology – Head and Neck Surgery, University of Udine, Policlinico Città di Udine, Viale Venezia 410, 33100 Udine, Italy. Fax: +39 0432 532179 e-mail: clorl@dsc.uniud.it

References

Hide All
Albrecht, H., Arzt, L. (1910) Beitrag zur Frage der gewebsurrung papillare. Cystadenoma in Lymphdrusen. Ztscher Pathol 4: 47. Quoted by: Singer, M. I., Applebaum, E. L., Loy, K. D. (1979) Heterotopic salivary tissue in the neck. Laryngoscope 89: 1772–1778.
Attie, J. N., Sciubba, J. J. (1981) Tumours of major and minor salivary glands. Current Problems in Surgery 18: 7475.
Badia, L., Weir, J. N., Robinson, A. C. (1996) Heterotopic pleomorphic adenoma of the external nose. Journal of Laryngology and Otology 110: 376378.
Batsakis, J. G. (1988) Accessory parotid gland. Annals of Otology, Rhinology and Laryngology 97: 434435.
Bernier, J. L., Bhaskar, S. N. (1958) Lymphoepithelial lesion of salivary glands. Histiogenesis and classification based on 186 cases. Cancer 11: 11561179.
Bhaskar, S. N. (1964) Acinic cell carcinoma of salivary glands–report of 21 cases. Oral Pathology 17: 6274.
Bothra, A. C., Agarwal, R. K., Dube, M. K., Bothra, S., Dixit, S. M. (1977) Mixed salivary tumour in heterotopic salivary tissue at the base of the neck. International Surgery 62: 228229.
Caironi, C., Re, S., Canali, B. (1981) Tumore misto a carico di ghiandola salivare ectopica. Presentazione di un caso. Minerva Chirurgica 36: 621624.
Cannon, C. R., Fechner, R. E. (1985) Pathologic quiz case 2. Archives of Otolaryngology 111: 702705.
Cannon, C. R., McLean, W. C. (1983) Adenoid cystic carcinoma of the middle ear and temporal bone. Otolaryngology – Head and Neck Surgery 91: 9699.
Cotelingam, J. D., Gerberi, M. P. (1983) Parotid heterotopia with pleomorphic adenoma. Report of an unusual neck mass. Archives of Otolaryngology 109: 563565.
Croce, A., Moretti, A., Bianchedi, M., D'Agostino, L., Angelucci, D., Diodoro, M. (1996) Tumore di Warthin ectopico cancerizzato: descrizione di un caso clinico e revisione della letteratura. Acta Otorhinolaryngologica Italica 16: 543549.
Curry, B., Taylor, C. W., Fisher, A. W. F. (1982) Salivary gland heterotopia. A unique cerebellopontine angle tumour. Archives of Pathology and Laboratory Medicine 106: 3538.
Dietert, S. (1975) Papillary cystadenoma lymphomatosum (Warthin's tumour) in patients in a general hospital over a 24-year period. American Journal of Clinical Pathology 63: 866875.
Ellies, M., Laskawi, C., Arglebe, C. (1998) Extraglandular Warthin's tumours: clinical evaluation and long-term follow-up. British Journal of Oral and Maxillofacial Surgery 36: 5253.
Evans, M. G., Rubin, S. Z. (1991) Pleomorphic adenoma arising in a salivary rest in childhood. Journal of Pediatric Surgery, 26: 13141315.
Ferlito, A., Baldan, M., Andretta, M., Blandamura, S., Pesavento, G., Piazza, M. (1991) Implantation of parotid plemorphic adenoma in the upper neck. ORL-Journal for Oto-Rhino-Laryngology and its Related Specialties 53: 165176.
Frommer, J. (1977) The human accessory parotid gland: its incidence, nature, and significance. Oral Surgery 43: 671676.
Gudbrandsson, F. K, Liston, S. L., Maisel, R. A. (1982) Heterotopic salivary tissue in the neck. Otolaryngology – Head and Neck Surgery 90: 279282.
Handler, S., Miller, R. H. (1978) Warthin's tumour: a rare case of a neck mass. Ear, Nose and Throat Journal 57: 3844.
Hata, T., Iga, H., Imai, S., Hirokawa, M. (1997) Heterotopic salivary gland adenocarcinoma in the cervical region. International Journal of Oral and Maxillofacial Surgery 26: 290292.
Hildebrand, O. (1895) Uber angeborne epithelial Scystn und Fistels des Halses. Archiv for Klin Chir 49: 167. Quoted by: Singer, M. I., Applebaum, E. L., Loy, K. D. (1979) Heterotopic salivary tissue in the neck. Laryngoscope 89: 1772–1778.
Hiranandani, L. H., Chandra, O., Melgiri, R. D., Hiranandani, N. L. (1966) Aberrant salivary tumours. (Report of four cases). Journal of Laryngology and Otology 80: 564570.
Horii, A., Honjo, Y., Nose, M., Ozaki, M., Yoshida, J.-I. (1997) Accessory parotid gland tumour: a case report. Auris Nasus Larynx 24: 105110.
Hulbert, J. C. (1978) Ectopic mixed salivary tumour in the neck. Journal of Laryngology and Otology 92: 533536.
Johnson, F. E., Spiro, R. H. (1979) Tumours arising in accessory parotid tissue. American Journal of Surgery 138: 576578.
Lange, M. J. (1974) Pleomorphic adenoma of the thyroid containing salivary gland cells with pseudocartilage and myoepithelial cells. International Surgery 59: 178179.
Lind, O., Bang, G. (1983) Heterotopic salivary gland tissue in the upper neck. International Journal of Oral Surgery 12: 201203.
Ludmer, B., Joachims, H. Z., Ben-Arie, J., Eliachar, I. (1981) Adenocarcinoma in heterotopic salivary tissue. Archives of Otolaryngology 107: 547548.
MacDougall, I. R. (1991) Thyroid scintigraphy. In The Thyroid – A Fundamental and Clinical Text (Braverman, L. E., Utiger, R. D., eds.), 6th Edition, J. B. Lippincott Company, Philadelphia, pp 445446.
Mair, L. W. S., Elverland, H. H., Knudsen, O. S. (1978) Heterotopic salivary pleomorphic adenoma. Journal of Otolaryngology 7: 158160.
Marcos Ordoñez, M., Sancho Alvarez, A., Morais Perez, D., Alvarez Gago, T. (1994) Mixed tumour in cervical salivary heterotopy. Acta Otorrinolaringologica Espanola 45: 387389.
Perzin, K. H., Livolsi, V. A. (1980) Acinic cell carcinoma arising in ectopic salivary gland tissue. Cancer 45: 967972.
Pesavento, G., Ferlito, A. (1976) Benign mixed tumour of heterotopic salivary gland tissue in upper neck. Report of a case with a review of the literature on heterotopic salivary gland tissue. Journal of Laryngology and Otology 90: 577584.
Rodgers, G. K., Felder, H., Yunis, E. J. (1991) Pleomorphic adenoma of cervical heterotopic salivary gland tissue: case report and review of neoplasms arising in cervical heterotopic salivary gland tissue. Otolaryngology – Head and Neck Surgery 104: 533536.
Rodriguez Bigas, M. A., Sako, K., Razack, M. S., Castillo, N. B. (1990) Extraparotid Warthin's tumour: an unexpected finding in three female patients. New York State Journal of Medicine 90: 465466.
Saeed, Y. M., Bassis, M. L. (1971) Mixed tumour of the middle ear. A case report. Archives of Otolaryngology 93: 433434.
Seifert, G. (1997) Primary salivary gland tumours in lymph nodes of the parotid gland. Report of 3 cases and review of the literature. Pathologe 18: 141146.
Seifert, G.Miehlke, A., Haubrich, J., Chulla, R. (1986) Diseases of the Salivary Glands: Pathology – Diagnosis – Treatment – Facial Nerve Surgery. Theme, Stuttgart, p 64.
Shinohara, M., Ikebe, T., Nakamura, S., Takenoshita, Y., Oka, M., Mori, M. (1996) Multiple pleomorphic adenomas arising in the parotid and submandibular lymph nodes. British Journal of Oral and Maxillofacial Surgery 34: 515519.
Singer, M. I., Applebaum, E. L., Loy, K. D. (1979) Heterotopic salivary tissue in the neck. Laryngoscope 89: 17721778.
Snyderman, C., Johnson, J. T., Barnes, E. L. (1986) Extraparotid Warthin's tumour. Otolaryngology – Head and Neck Surgery 94: 169175.
Surana, R., Moloney, R., Fitzgerald, R. J. (1993) Tumours of heterotopic salivary tissue in the upper cervical region in children. Surgery of Oncology 2: 133136.
Tay, H. L., Howitt, R. J. (1995) Heterotopic pleomorphic adenoma in the neck. Journal of Laryngology and Otology 109: 445448.
Toh, H., Kodama, J., Fukuda, J., Rittman, B., Mackenzie, I. (1993) Incidence and histology of human accessory parotid glands. Anatomical Record 236: 586590.
Tuta, J. A., Apfelnbach, G. L. (1942) Papillary adenocystoma lymphomatosum of the neck. American Journal of Surgery 56: 504506.
Warnock, G. R., Jensen, J. L., Kratochvil, F. J. (1991) Developmental diseases. In Surgical Pathology of the Salivary Glands. (Ellis, G. L., Auclair, P. L., Gnepp, D. R., eds.) W. B. Saunders Company, Philadelphia, pp 1025.
Willis, R. A. (1968) Some unusual developmental heterotopias. British Medical Journal 3: 267272.
Wilson, D. F., MacEntee, M. I. (1974) Papillary cystoadenoma of ectopic minor salivary gland origin. Oral Surgery, Oral Medicine, Oral Patjology 37: 915918.
Worthington, Ph. (1982) Mischtumor im heterotopen Speicheldrüsengewebe des Halses. Dtsch Z Mund-Kiefer-Gesichts-Chir 6: 381. Quoted by: Seifert, G., Miehlke, A., Haubrich, J., Chilla, R. Diseases of the Salivary Glands: Pathology – diagnosis – Treatment – Facial Nerve Surgery. Thieme, Stuttgart, p 64.
Yacoub, U., Becher Carstens, P. H., Biscopink, R. J., McMurry, G. T. (1981) Acinic-cell tumour in ectopic salivary-gland tissue. Archives of Pathology and Laboratory Medicine 105: 500501. (Letter to Editor).
Yoo, G. H., Eisele, D. W., Askin, F. B., Driben, J. S., Johns, M. E. (1994) Warthin's tumour: a 40-year experience at the Johns Hopkins Hospital. Laryngoscope 104: 799803.
Yoshida, F., Morikawa, I., Shin, T., Matsuo, K., Tomita, M., Nakaai, K. (1986) Pleomorphic adenoma of the neck: report of two cases. Nippon Jibünkoka Gakkai Kaiho 89: 689694.
Zajtchuk, J. T., Patow, C. A., Hyams, V. J. (1982) Cervical heterotopic salivary gland neoplasms: a diagnostic dilemma. Otolaryngology – Head and Neck Surgery 90: 178181.

Keywords

Metrics

Full text views

Total number of HTML views: 0
Total number of PDF views: 0 *
Loading metrics...

Abstract views

Total abstract views: 0 *
Loading metrics...

* Views captured on Cambridge Core between <date>. This data will be updated every 24 hours.

Usage data cannot currently be displayed