Skip to main content Accessibility help
×
Home

Rapidly progressing giant invasive prolactinoma

  • R H Care (a1), V S Sunkaraneni (a2), J Theaker (a3) and P G Harries (a4)

Abstract

Objective:

We report an extremely rare case of a giant invasive prolactinoma presenting as a nasopharyngeal tumour.

Method:

Case report and literature review regarding giant prolactinoma.

Results:

Giant prolactinoma is a rare form of prolactinoma which accounts for 0.5–4.4 per cent of all pituitary tumours. It is more common in men and generally presents with symptoms of endocrine disturbance or neurological deficit.

Conclusion:

To our knowledge, this is the first report of giant prolactinoma presenting with symptoms of sinusitis and nasopharyngeal tumour.

Copyright

Corresponding author

Address for correspondence: Dr Rachel Care, Christchurch Hospital, 2 Riccarton Avenue, Addington 8011, New Zealand E-mail: rachelcare@doctors.net.uk

References

Hide All
1 Gillam, MP, Molitch, ME, Lombardi, G, Colao, A. Advances in the treatment of prolactinomas. Endocr Rev 2006;27:485534
2 Murphy, FY, Vesely, DL, Jordan, RM, Flanigan, S, Kohler, PO. Giant invasive prolactinomas. Am J Med 1987;83:9951002
3 Colao, A, Sarno, AD, Cappabianca, P, Briganti, F, Pivonello, R, Somma, CD et al. Gender differences in the prevalence, clinical features and response to cabergoline in hyperprolactinemia. Eur J Endocrinol 2003;148:325–31
4 Minniti, G, Jaffrain-Rea, ML, Santoro, A, Esposito, V, Ferrante, L, Delfini, R et al. Giant prolactinomas presenting as skull base tumors. Surg Neurol 2002;57:99103
5 Dafer, RM, Jay, WM. Headache and the eye. Curr Opin Ophthalmol 2009;20:520–4
6 Ciccarelli, E, Camanni, F. Diagnosis and drug therapy of prolactinoma. Drugs 1996;51:954–65
7 Cho, EH, Lee, SA, Chung, JY, Koh, EH, Cho, YH, Kim, JH et al. Efficacy and safety of cabergoline as first line treatment for invasive giant prolactinoma. J Korean Med Sci 2009;24:874–8
8 Kreutzer, J, Buslei, R, Wallaschofski, H, Hofmann, B, Nimsky, C, Fahlbusch, R et al. Operative treatment of prolactinomas: indications and results in a current consecutive series of 212 patients. Eur J Endocrinol 2008;158:1118

Keywords

Rapidly progressing giant invasive prolactinoma

  • R H Care (a1), V S Sunkaraneni (a2), J Theaker (a3) and P G Harries (a4)

Metrics

Full text views

Total number of HTML views: 0
Total number of PDF views: 0 *
Loading metrics...

Abstract views

Total abstract views: 0 *
Loading metrics...

* Views captured on Cambridge Core between <date>. This data will be updated every 24 hours.

Usage data cannot currently be displayed