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A preliminary report on the combination of initial chemotherapy and radiotherapy for advanced head and neck cancer

Published online by Cambridge University Press:  29 June 2007

R. Sergeant  and
G. Deutsch
R. Sergeant
Affiliation:
Brighton
G. Deutsch
Affiliation:
Brighton
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Abstract

A Retrospective review of 45 patients with advanced squamous cell carcinoma of the head and neck treated by a combination of initial chemotherapy (Price and Hill Schedule A) followed by radiotherapy is presented. The regime produced excellent immediate palliation with a tumour control of 50 per cent, and a disease-free survival of 33 per cent at one year and 27 per cent at two years. Treatment morbidity was minimal in an aged patient group.

Type
Research Article
Information
The Journal of Laryngology & Otology , Volume 95 , Issue 1 , January 1981 , pp. 69 - 73
Copyright
Copyright © JLO (1984) Limited 1981

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References

REFERENCES

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O'Connor, A. D., Clifford, P., Durden-Smith, J., Edwards, E., Hollis, B. A. and Dalley, V. M. (1977) Synchronous VBM and radiotherapy in the treatment of squamous cell carcinoma of the head and neck. Clinical Otolaryngology, 1, 347.CrossRefGoogle Scholar
Price, L. A., Hill, B. T., Calvert, A. H., Shaw, H. J. and Hughes, K. B. (1975) Kinetically-based multiple drug treatment for advanced head and neck cancer. British Medical Journal, 3, 10–11.CrossRefGoogle ScholarPubMed