Skip to main content Accessibility help
×
Home

Olfaction, pheromones and life

  • E E Hoskison (a1)

Abstract

Background:

From an evolutionary standpoint, olfaction is one of the oldest senses, and one that affects all aspects of life. This review discusses the influence of olfaction and pheromones on life.

Methods:

A literature search was conducted using MEDLINE (1966–2012), Embase (1988–2012), The Cochrane Library (1993–2013) and Ovid (1966–2012).

Results:

Olfaction plays an important role in life, from infancy through to adulthood and declining health in old age. Culture, memories and emotions, which add to life's complexity and overall enjoyment, are also influenced by olfaction.

Conclusion:

Olfaction has a chronological influence on life, affecting all aspects from the cradle to the grave; it plays a role in the quality of life as a key ingredient of human evolution, survival and enjoyment.

Copyright

Corresponding author

Address for correspondence: Miss E E Hoskison, Department of Otorhinolaryngology, Head and Neck Surgery, Schulich School of Nottingham University Hospitals NHS Trust, Nottingham, NG7 2UHUK Fax: +44 0115 9709758 E-mail: emmahoskison@hotmail.com

References

Hide All
1Xenophon. Symposium, trans. Bartlett, RC, Pangle, T, Amber, W. Ithaca, NY: Cornell University Press: The Agora Editions, 1996;37
2Philpott, CM, Bennett, A, Murty, GE. A brief history of olfaction and olfactometry. J Laryngol Otol 2008;122:657–62
3Shakespeare, W. The Oxford Shakespeare: As You Like It (Oxford World's Classics). Brissenden, A, ed. Oxford: Oxford University Press, 2008;152
4Ressler, KJ, Sullivan, SL, Buck, LB. A molecular dissection of spatial patterning in the olfactory system. Curr Opin Neurobiol 1994;4:588–96
5Takagi, SF. Human Olfaction. Tokyo: University of Tokyo Press, 1989
6Doty, RL. Handbook of Olfaction and Gustation, 2nd edn.New York: Marcel Dekker, 2003
7Karlson, P, Luscher, M. ‘Pheromones’: a new term for a class of biologically active substances. Nature 1959;183:55–6
8Cuvier, G. Report made on the memoir of M Jacobsen entitled: anatomical description of an organ observed in mammals [in French]. Ann Mus Hist Nat Paris 1812;18:412–24
9Johnson, A, Josephson, R, Hawke, M. Clinical and histological evidence for the presence of the vomeronasal (Jacobson's) organ in adult humans. J Otolaryngol 1985;14:71–9
10Doty, RL. Olfaction. Annu Rev Psychol 2001;52:423–52
11Boehm, N, Roos, J, Gasser, B. Luteinizing hormone-releasing hormone (LHRH)-expressing cells in the nasal septum of human fetuses. Brain Res Dev Brain Res 1994;82:175–80
12Brennan, P, Zufall, F. Pheromonal communication in vertebrates. Nature 2006;444:308–15
13Wallis Budge, EA. The Egyptian Book of the Dead: the hieroglyphic transcript of the Papyrus of Ani. New Hyde Park, NY: University Books, 1960
14Allen, JP. The Art of Medicine in Ancient Egypt. New York: Metropolitan Museum of Art, 2005
15Classen, C, Howes, D, Synnott, A. Aroma: the Cultural History of Smell. London/New York: Routledge, 1994
16Freud, S. Civilization and its Discontents, trans. Strachey, J. New York: WW Norton, 1961;96–7
17Darwin, C. The Descent of Man, and Selection in Relation to Sex. London: John Murray, 1871
18Bhutta, MF. Sex and the nose: human pheromonal responses. J R Soc Med 2007;100:268–74
19Van Der Lee, S, Boot, LM. Spontaneous pseudopregnancy in mice. Acta Physiol Pharmacol Neerl 1955;4:442–4
20Bruce, HM. A block to pregnancy in the mouse caused by proximity of strange males. J Reprod Fertil 1960;1:96103
21McClintock, MK. Menstrual synchrony and suppression. Nature 1971;229:244–5
22Preti, G, Cutler, WB, Garcia, CR, Huggins, GR, Lawley, HJ. Human axillary secretions influence women's menstrual cycles: the role of donor extract of females. Horm Behav 1986;20:474–82
23Russell, MJ. Human olfactory communication. Nature 1976;260:520–2
24Porter, RH, Moore, JD. Human kin recognition by olfactory cues. Physiol Behav 1981;27:493–5
25Cernoch, JM, Porter, RH. Recognition of maternal axillary odors by infants. Child Dev 1985;56:1593–8
26Blanchard, DC, Blanchard, RJ, Griebel, G. Defensive responses to predator threat in the rat and mouse. Curr Protoc Neurosci 2005;8:8.19
27Pinnaduwage, LA, Gehl, AC, Allman, SL, Johansson, A, Boisen, A. Minature sensor suitable for electronic nose applications. Rev Sci Instrum 2007;78:055101
28Kallmann, FJ, Schönfeld, WA, Barrera, SE. The genetic aspects of primary eunuchoidism. Am J Ment Defic 1944;48:203–36
29Welge-Lüssen, A. Ageing, neurodegeneration, and olfactory and gustatory loss. B-ENT 2009;5(suppl 13):129–32
30Neurological and Communicative Disorders and Stroke Council. Report of the Panel on Communicative Disorders to the National Advisory Neurological and Communicative Disorders and Stroke Council. Washington, DC: National Institute of Health, 1979
31Lund, VJ, Preziosi, P, Hercberg, S, Hamoir, M, Dubreuil, C, Pessey, JJ et al. Yearly incidence of rhinitis, nasal bleeding, and other nasal symptoms in mature women. Rhinology 2006;44:2631
32Ciofalo, A, Filiaci, F, Romeo, R, Zambetti, G, Vestri, AR. Epidemiological aspects of olfactory dysfunction. Rhinology 2006;44:7882
33Holbrook, EH, Leopold, DA. An updated review of clinical olfaction. Curr Opin Otolaryngol Head Neck Surg 2006;14:23–8
34Rowe-Jones, JM, Medcalf, M, Durham, SR, Richards, DH, Mackay, IS. Functional endoscopic sinus surgery: 5 year follow up and results of a prospective, randomised, stratified, double-blind, placebo controlled study of postoperative fluticasone propionate aqueous nasal spray. Rhinology 2005;43:210
35Doty, RL. Olfactory capacities in aging and Alzheimer's disease. Psychophysical and anatomic considerations. Ann N Y Acad Sci 1991;640:20–7
36Harrison, PJ, Pearson, RC. Olfaction and psychiatry. Br J Psychiatry 1989;155:822–8
37Turetsky, BI, Hahn, CG, Borgmann-Winter, K, Moberg, PJ. Scents and nonsense: olfactory dysfunction in schizophrenia. Schizophr Bull 2009;35:1117–31
38Jones, N, Rog, D. Olfaction: a review. J Laryngol Otol 1998;112:1124
39Hong, JH, Omur-Ozbek, P, Stanek, BT, Dietrich, AM, Duncan, SE, Lee, YW et al. Taste and odor abnormalities in cancer patients. J Support Oncol 2009;7:5865
40Lund, VJ, Stammberger, H, Nicolai, P, Castelnuovo, P, Beal, T, Beham, A et al. European position paper on endoscopic management of tumours of the nose, paranasal sinuses and skull base. Rhinol Suppl 2010;22:1143
41Willis, CM, Church, SM, Guest, CM, Cook, WA, McCarthy, N, Bransbury, AJ et al. Olfactory detection of human bladder cancer by dogs: proof of principle study. BMJ 2004;329:712
42Chapman, EA, Thomas, PS, Stone, E, Lewis, C, Yates, DH. A breath test for malignant mesothelioma using an electronic nose. Eur Respir J 2012;40:448–54

Keywords

Olfaction, pheromones and life

  • E E Hoskison (a1)

Metrics

Full text views

Total number of HTML views: 0
Total number of PDF views: 0 *
Loading metrics...

Abstract views

Total abstract views: 0 *
Loading metrics...

* Views captured on Cambridge Core between <date>. This data will be updated every 24 hours.

Usage data cannot currently be displayed