Hostname: page-component-8448b6f56d-42gr6 Total loading time: 0 Render date: 2024-04-19T11:12:43.827Z Has data issue: false hasContentIssue false
  • English
  • Français

Mucoepidermoid carcinoma of the larynx

Published online by Cambridge University Press:  29 June 2007

V. L. Cumberworth ,
A. Narula ,
K. A. MacLennan  and
P. J. Bradley
V. L. Cumberworth*
Affiliation:
Head and Neck Oncology Clinic, Department of Otolaryngology, University Hospital, Queen's Medical Centre, Nottingham.
A. Narula
Affiliation:
Head and Neck Oncology Clinic, Department of Otolaryngology, University Hospital, Queen's Medical Centre, Nottingham.
K. A. MacLennan
Affiliation:
Head and Neck Oncology Clinic, Department of Otolaryngology, University Hospital, Queen's Medical Centre, Nottingham.
P. J. Bradley
Affiliation:
Head and Neck Oncology Clinic, Department of Otolaryngology, University Hospital, Queen's Medical Centre, Nottingham.
*
Mr. V. L. Cumberworth, 34 Penrith Avenue, Shepshed, Nr. Loughborough, Leics. LE12 9NB.
Get access Rights & Permissions [Opens in a new window]

Abstract

We report two cases of poorly differentiated mucoepidermoid carcinoma of the larynx which both remain well after surgical management. The first underwent a radical neck dissection for recurrent disease following radiotherapy and the second a total laryngectomy with elective post-operative radiotherapy.

Although well differentiated (‘low grade’) mucoepidermoid tumours of the larynx may respond to radiotherapy surgical management is generally recommended for all grades of such tumours especially for poorly differentiated (‘high grade’) tumours. Elective post-operative radiotherapy is often advocated for high grade tumours; radical neck dissection is generally undertaken only in the presence of lymphadenopathy, although elective radical neck dissection has been proposed for high grade tumours. These cases emphasise the value of comprehensive surgical management for this condition.

Such laryngeal tumours are difficult to diagnose histologically from biopsy and are often initially reported as squamous cell carcinoma.

Type
Clinical Records
Information
The Journal of Laryngology & Otology , Volume 103 , Issue 4 , April 1989 , pp. 420 - 423
Copyright
Copyright © JLO (1984) Limited 1989

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Arcidiacono, D. G. and Loineo, D. G. (1963) Tumori muco epidermoidali salivari. Clinica Oto-Rino-Laringoiatrica, 15: 95–108.Google Scholar
Barnes, L. (1985) Mucoepidermoid carcinoma, in Surgical Pathology of the Head and Neck, volume 1, Marcel Dekker, Inc. pp.187.Google Scholar
Binder, W. J., Som, P. S., Kaneko, M. and Biller, H. F. (1980) Mucoepidermoid carcinoma of the larynx. A case report and review of the literature. Annals of Otology, Rhinology and Laryngology, 89: 103–107.CrossRefGoogle ScholarPubMed
Bossart, A. (1945) Schweizerische Monatschrift. Zahnheilkunde, 55: 91.Google Scholar
Cady, B., Rippey, J. H. and Frazell, E. L. (1968) Non-epidermoid cancer of the larynx. Annals of Surgery, 167: 116–120.CrossRefGoogle ScholarPubMed
Davis, W. E. and Beck, M. R. (1975) Mucoepidermoid carcinoma of the larynx—A case report. Eye, Ear, Nose and Throat Monthly, 54: 394–396.Google ScholarPubMed
Ferlito, A., Recher, G. and Bottin, R. (1981) Mucoepidermoid carcinoma of the larynx. A clinicopathological study of 11 cases with review of the literature. ORL, 43: 280–299.CrossRefGoogle ScholarPubMed
Gadomski, S. P., Zwillenberg, D. and Choi, H. Y. (1986) Non-epidermoid carcinoma of the larynx. Otolaryngology—Head and Neck Surgery, 95: 558–565.CrossRefGoogle ScholarPubMed
Gatti, W. M. and Erkman-Balis, B. (1980) Mucoepidermoid carcinoma of the larynx. Archives of Otolaryngology, 106: 52–53.CrossRefGoogle ScholarPubMed
Hamlyn, P. J., O'Brien, C. J. and Shaw, H. J. (1986) Uncommon malignant tumours of the larynx. A 35 year review. Journal of Laryngology and Otology, 100: 1163–1168.CrossRefGoogle ScholarPubMed
Kaznelson, D. J. and Schindel, J. (1979) Mucoepidermoid carcinoma of the air passages. Laryngoscope, 89: 115–121.CrossRefGoogle ScholarPubMed
Koike, S., Ogawara, T., Moriwaki, S., Aoki, T. and Watanabe, S. (1978) Three cases of adenocarcinoma of the larynx. Practica Otologica Kyoto, 71: 1101–1107.CrossRefGoogle Scholar
Marcial-Rojas, R. A. and Sommers, S. C. (1954) Differentiated mucoepidermoid tumors of salivary glands. Archives of Otolaryngology, 59: 135–140.CrossRefGoogle ScholarPubMed
Muratti, G. (1969) Epitelioma muco-epidermoide della laringe. Archivio Italiano di Otologia, Rinologia, Laringologia and Patologia Cervico-Facciale, 80: 131–153.Google Scholar
Okinaka, Y. and Sekitani, T. (1984) Mucoepidermoid carcinoma of the vocal cord. Report of a case. ORL, 46: 139–146.CrossRefGoogle ScholarPubMed
Rosenfeld, L. R., Sessions, D. G., McSwain, B. and Graves, H. (1966) Malignant tumors of salivary gland origin: 37 year review of 184 cases. Annals of Surgery, 163: 726–735.CrossRefGoogle ScholarPubMed
Sabri, J. A. and Hajjar, H. A. (1967) Malignant mixed tumor of the vocal cord. Archives of Otolaryngology, 85: 118–120.Google ScholarPubMed
Seo, I. S., Tomich, C. E., Warfel, K. A. and Hull, M. T. (1980) Clear cell carcinoma of the larynx. A variant of muco epidermoid carcinoma. Annals of Otology, Rhinology and Laryngology, 89: 168–172.CrossRefGoogle Scholar
Sessions, P. E., Murray, J. P., Bower, W. C. and Ogura, J. H. (1975) Adenocarcinoma of the larynx. Canadian Journal of Otolaryngology, 4: 293–296.Google ScholarPubMed
Spiro, R. H., Lewis, J. S., Hadju, S. I. and Strong, E. W. (1976) Mucus gland tumors of the larynx and laryngopharynx. Annals of Otology, Rhinology and Laryngology, 85: 498–503.CrossRefGoogle ScholarPubMed
Stewart, F. W., Foote, F. W. and Becker, W. F. (1945) Mucoepidermoid tumors of salivary glands. Annals of Surgery, 122: 820–844.CrossRefGoogle ScholarPubMed
Tandon, D. A., Deka, B. C. and Chowdhury, C. (1985) Mucoepidermoid carcinoma of the larynx. Ear, Nose and Throat Journal, 64: 555–557.Google ScholarPubMed
Thomas, K. (1971) Mucoepidermoid carcinoma of the larynx. Journal of Laryngology and Otology, 85: 261–267.CrossRefGoogle ScholarPubMed
Tomita, T., Talbott, L. and Watanabe, I. (1977) Mucoepidermoid carcinoma of the subglottis. An ultrastructural study. Archives of Pathology and Laboratory Medicine, 101: 145–148.Google ScholarPubMed
Whicker, J. H., Neel, H. B., Weiland, L. H. and Devine, K. D. (1974) Adenocarcinoma of the larynx. Annals of Otology, Rhinology and Laryngology, 83: 487–490.CrossRefGoogle ScholarPubMed