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Mast cell ultrastructure in the adenoids of children with and without secretory otitis media

Published online by Cambridge University Press:  29 June 2007

Adrian Drake-Lee ,
Jacqueline Price  and
R. Varley
Adrian Drake-Lee*
Affiliation:
Department of Otolaryngology, Queen Elizabeth Hospital, Birmingham.
Jacqueline Price
Affiliation:
Department of Electron Microscopy, Royal United Hospital, Bath.
R. Varley
Affiliation:
Department of Electron Microscopy, Royal United Hospital, Bath.
*
Mr Adrian Drake-Lee, Department of Otolaryngology, Queen Elizabeth Hospital, Birmingham B15 2TH.
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Abstract

This study was designed to compare the differences in morphology of the mast cells from the adenoid in children with otitis media with effusion (OME) and those from children with recurrent tonsillitis. Tissue for electron microscopy was prepared in the standard manner and between three and 10 blocks were examined for each child. All the mast cells with nuclei were photographed and the condition of the granules noted. The number of electron dense granules in each cell was assessed on a scale between zero and 10. Sixteen unselected children with OME were compared with 19 children with recurrent tonsillitis. There were no obvious differences in the degree of degranulation between the two groups although there was more vacuolation than reviously described in the normal nose but less than in those patients with perennial allergic rhinitis. Allergy and mast cell reactions do not seem to predispose to OME. It was concluded that the adenoids are not the ideal tissue in which to study normal mast cells.

Keywords

Otitis media with effusionMast cellsultrastructureAdenoidTonsil
Type
Main Articles
Information
The Journal of Laryngology & Otology , Volume 108 , Issue 12 , December 1994 , pp. 1058 - 1063
Copyright
Copyright © JLO (1984) Limited 1994

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