Hostname: page-component-77c89778f8-vpsfw Total loading time: 0 Render date: 2024-07-17T00:52:15.785Z Has data issue: false hasContentIssue false
  • English
  • Français

Management of clinically diagnosed subacute rhinosinusitis in children under the age of two years: a randomized, controlled study

Published online by Cambridge University Press:  29 June 2006

D M El-Hennawi ,
A S Abou-Halawa  and
S R Zaher
D M El-Hennawi
Affiliation:
Otorhinolaryngology Department, Suez Canal University, Ismailia, Egypt
A S Abou-Halawa
Affiliation:
Otorhinolaryngology Department, Suez Canal University, Ismailia, Egypt
S R Zaher
Affiliation:
Paediatrics Department, Alexandria University Hospital, Alexandria, Egypt
Get access Rights & Permissions [Opens in a new window]

Abstract

Background: In children, a diagnosis of rhinosinusitis is usually made on clinical grounds. Subacute rhinosinusitis (SRS) may be the cause of persistent cough, low-grade fever, snoring, ear problems and difficult feeding in children under the age of two years.

Objective: To compare the efficacy of culture-based antibiotics and empiric amoxicillin–clavulanate (40 mg/kg/day) in treating SRS in children under the age of two years.

Study design: Randomized, controlled study.

Population: Sixty children with persistent nasal discharge and nasal obstruction (and other related symptoms) for 30–90 days.

Methods: Group one (n = 30) received culture-based antibiotics and group two (n = 30) were treated empirically with 40 mg/kg/day of amoxicillin–clavulanate. Treatment was continued for two weeks.

Results: At the end of the three-week follow-up period, statistically significant greater improvements in nasal obstruction (p = 0.037) and nasal discharge (p = 0.003) were seen in group one compared with group two.

Conclusion: culture-based antibiotics were more efficacious than empiric amoxicillin–clavulanate (40 mg/kg/day) in treating SRS in children under the age of two years.

Keywords

SinusitisBacteriologyChildAntibiotics
Type
Main Articles
Information
The Journal of Laryngology & Otology , Volume 120 , Issue 10 , October 2006 , pp. 845 - 848
Copyright
2006 JLO (1984) Limited

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)