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Linkage analysis and the tracking of susceptibility genes

  • Kevin Stopps (a1) and Fiona Macdonald (a1)

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Corresponding author

Address for correspondence:Molecular Genetics Laboratory, West Midlands Regional Genetics Service, Birmingham Women's Hospital, Metchley Park Road, Edgbaston, Birmingham B15 2TG.

References

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Ott, J. (1991) Analysis of Human Genetic Linkage. Revised Edition. John Hopkins University Press, Baltimore.
Strachan, T., Read, A. P. (1996) Human Molecular Genetics. Bios Scientific Publishers, Oxford.
Donis-Keller, H., Green, P., Helms, C., Cartinhour, S., Weiffenbach, B., Stephens, K., Keith, T. P., et al. (1987) A genetic linkage map of the human genome. Cell 51: 319337.
Gusella, J. F., Wexler, N. S., Conneally, P. M., Naylor, S. L., Anderson, M. A., Tanzi, R. E., Watkins, P. C., et al. (1983) A polymorphic DNA marker genetically linked to Huntington's disease. Nature 306: 234238.
Lathrop, G. M., Lalouel, J. M., Julier, C., Ott, J. (1984) Strategies for multilocus linkage analysis in humans. Proceedings of the National Academy of Sciences. United States of America 81: 34433446.
Miki, Y., Swensen, J., Shattuck-Eidens, D., Futreal, A. P., Harshman, K., Tavtgian, S., Liu, Q., et al. (1994) A strong candidate for the breast and ovarian cancer susceptibility gene BRCA1. Science 266: 6671.
Murray, J. C., Buetow, K. H., Weber, J. L., Ludwigsen, S., Scherpbier-Heddema, T., Manion, F., Quillen, J., et al. (1994) A comprehensive human linkage map with centi-morgan density. Co-operative Human Linkage Center (CHLC). Science 265: 20492054.
Ott, J. (1974) Estimation of the recombination fraction in human pedigrees: efficient computation of the likelihood for human linkage studies. American Journal of Human Genetics 26: 588597.
Wooster, R., Bignell, G., Lancaster, J., Swift, S., Seal, S., Mangion, J., Collins, N., et al. (1995) Identification of the breast cancer susceptibility gene BRCA2. Nature 378: 789792.

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