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Intra-operative application of confocal endomicroscopy using a rigid endoscope

Published online by Cambridge University Press:  23 April 2013

T Just  and
H W Pau
T Just*
Affiliation:
Department of Otorhinolaryngology, University of Rostock, Germany
H W Pau
Affiliation:
Department of Otorhinolaryngology, University of Rostock, Germany
*
Address for correspondence: Dr Tino Just, Department of Otorhinolaryngology, Head and Neck Surgery, University of Rostock, Doberaner Str 137–139, D-18057 Rostock, Germany Fax: +49 381 494 8302 E-mail: tino.just@med.uni-rostock.de
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Abstract

Objective:

To introduce the application of confocal endomicroscopy during microlaryngoscopy, to enable intra-operative evaluation of human laryngeal epithelium.

Methods:

A rigid endoscope was connected to the scanner head of a Heidelberg Retina Tomograph II confocal laser scanning system via an adapter. The endoscope was gently placed on the surface of a vocal fold through a laryngoscope during microlaryngoscopy.

Results:

The application of confocal endomicroscopy using a rigid endoscope enabled technical improvements (i.e. improved image quality, automatic volume scan, and reduced tissue pressure due to the presence of a perforation plate with central hole at the end of the endoscope) which permitted greater sensitivity and improved handling. Confocal endomicroscopy provided good quality, in vivo, en-face images and enabled an assessment of laryngeal epithelium volume.

Conclusion:

This method enables the surgeon to monitor epithelial changes in pre-malignant lesions. The combination of confocal endomicroscopy together with optical coherence tomography (as a complementary technique that provides optical cross-sections) should be further explored in a formal clinicopathological study.

Keywords

Confocal EndomicroscopyConfocal MicroscopyRigid EndoscopeLarynxVocal Cord
Type
Short Communications
Information
The Journal of Laryngology & Otology , Volume 127 , Issue 6 , June 2013 , pp. 599 - 604
Copyright
Copyright © JLO (1984) Limited 2013 

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