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Cervical radiculopathy due to intra-arterial infusion of cisplatin

Published online by Cambridge University Press:  08 March 2006

Toshiro Nishimura ,
Jun-Ichiro Sanada  and
Mitsuru Furukawa
Toshiro Nishimura
Affiliation:
Department of Otolaryngology, Kanazawa University Graduate School of Medicine, Kanazawa, Japan
Jun-Ichiro Sanada
Affiliation:
Department of Radiology, Kanazawa University Graduate School of Medicine, Kanazawa, Japan
Mitsuru Furukawa
Affiliation:
Department of Otolaryngology, Kanazawa University Graduate School of Medicine, Kanazawa, Japan
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Abstract

A 55-year-old man with cervical radiculopathy (C5–C8) was referred to us following intra-arterial infusion of cisplatin (CDDP) because of a recurrent neck mass of laryngeal cancer. Three hours after the CDDP infusion, he had noticed general weakness of the left upper extremity and hypoaesthesia of the lateral side of the upper and lower arm. The next day he was diagnosed with left cervical radiculopathy of C5 to C8, which improved gradually and had resolved completely six months after the infusion. Even with proper positioning of the infusion catheter to minimize potential complications, for anatomical reasons there are always some risks of neural injury with intra-arterial infusion from branches of the subclavian artery. This procedure should be carefully indicated in the case of a large neck tumour that is perfused from the major branches of the subclavian artery.

Keywords

CisplatinIntra-Arterial InfusionsRadiculopathy
Type
Research Article
Information
The Journal of Laryngology & Otology , Volume 119 , Issue 8 , August 2005 , pp. 649 - 650
Copyright
© 2005 Royal Society of Medicine Press

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