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Auditory brainstem evoked responses in hyperlipidaemia: effect of various lipid fractions on auditory function

  • J S Thakur (a1), N K Mohindroo (a1), M S Vasanthalakshmi (a2), N Kashyap (a1), R K Azad (a1) and D R Sharma (a1)...

Abstract

Objective:

To evaluate the effect of different lipid fractions on auditory brainstem evoked responses in hyperlipidaemia.

Method:

We conducted a single institution (medical college), prospective, cross-sectional study of 25 hyperlipidaemic patients and 25 normolipidaemic controls, all with a normal hearing threshold on pure tone audiometry. Brainstem evoked response audiometry results were recorded in both groups. The hyperlipidaemic group were further divided into two subgroups, based on the serum value of each lipid fraction: those with less than and those with greater than the mean serum value. These two subgroups were further compared with the control group.

Results:

The hyperlipidaemic and normolipidaemic groups had statistically significant differences for all audiometry waves apart from the wave I and the III–V interpeak latencies. The subgroups had a statistically significant difference in brainstem evoked responses. We found a statistically significant association between low-density lipoproteins and many waveforms in the hyperlipidaemic group.

Conclusion:

We found that low-density lipoproteins were significantly associated with many waveforms in hyperlipidaemic patients. Thus, low-density lipoproteins may be important in auditory dysfunction.

Copyright

Corresponding author

Address for correspondence: Dr J S Thakur, Department of Otolaryngology-Head and Neck Surgery, Indira Gandhi Medical College, Shimla 171001, India Fax: 91 177 2800224 E-mail: anujagdeep@yahoo.co.in

References

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Keywords

Auditory brainstem evoked responses in hyperlipidaemia: effect of various lipid fractions on auditory function

  • J S Thakur (a1), N K Mohindroo (a1), M S Vasanthalakshmi (a2), N Kashyap (a1), R K Azad (a1) and D R Sharma (a1)...

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