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An individualised treatment algorithm for tumour stage 1 glottic squamous cell carcinoma

  • U Aydil (a1), M Akmansu (a2), Y Kizil (a1), Ö Yazici (a2), S Üstün (a1), F Karaloğlu (a1) and A Köybaşioğlu (a1)...

Abstract

Objective:

To report and discuss the outcome of a treatment algorithm for patients with tumour stage 1 glottic squamous cell carcinoma.

Method:

A retrospective outcome analysis study was performed using data from a tertiary referral centre.

Results:

Sixty-nine patients were treated with radiotherapy and 26 with surgery, in accordance with the treatment algorithm. Five-year overall survival rates were the same for both treatment groups (92 per cent). Five-year disease-specific survival rates were 100 per cent for surgery, 98 per cent for radiotherapy and 99 per cent overall. The overall 5-year laryngeal preservation rate was 89.1 per cent, being 95.7 per cent for surgery patients and 86.7 per cent for radiotherapy patients (p = 0.502). There was no significant association between laryngeal preservation rates and age (p = 0.779), anterior commissure involvement (p = 0.081), tumour stage (1a or 1b) (p = 0.266) or treatment modality (surgery or radiotherapy; p = 0.220). There was no significant difference in local recurrence rates between the two treatment groups (19.3 per cent for radiotherapy vs 10.0 per cent for surgery; p = 0.220). The overall 5-year regional recurrence rate was 1.2 per cent.

Conclusion:

Tumour stage 1 glottic carcinoma can be managed with different treatment modalities, following an individualised treatment algorithm, with results comparable to published outcomes.

Copyright

Corresponding author

Address for correspondence: Dr Utku Aydil, Gazi Ün Tıp Fak KBB AD, 06500 Beşevler, Ankara, Turkey Fax: +90 312 202 4357 E-mail: utkuaydil@yahoo.com

References

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Keywords

An individualised treatment algorithm for tumour stage 1 glottic squamous cell carcinoma

  • U Aydil (a1), M Akmansu (a2), Y Kizil (a1), Ö Yazici (a2), S Üstün (a1), F Karaloğlu (a1) and A Köybaşioğlu (a1)...

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