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Immunophenotypes of the palatal tonsil lymphocytes in Cowden's disease

Published online by Cambridge University Press:  29 June 2007

Yasuyuki Kimura ,
Takaki Miwa  and
Mituru Furukawa
Yasuyuki Kimura*
Affiliation:
Kanazama, Japan
Takaki Miwa
Affiliation:
Kanazama, Japan
Mituru Furukawa
Affiliation:
Kanazama, Japan
*
Dr Yasuyuki Kimura, Dept. of Otolaryngology, School of Medicine, Kanazawa Univeristy, 13-1 Takaramachi, Kanazawa, 920, Japan
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Abstract

Cowden's disease is characterized by multiple hamartomas and neoplasias of ectodermal, mesodermal and endodermal origin. A case of a 22-year-old man suffering from nocturnal dyspnoea is reported. The patient had a large number of hyperkeratotic, lichenoid papules, scattered over the right side of the trunk, back and palm. In his oral cavity, papules were present on the gingiva and hard palate. The patient was operated on for tonsillar hypertrophy and for excluding the possibility of malignant lymphoma. An examination of immunophenotypes of the palatal tonsil lymphocytes revealed B-cell proliferation and poly-clonal immunoglobulin.

Keywords

Cowden's diseaseImmunophenotypesPalatal tonsil
Type
Clinical Records
Information
The Journal of Laryngology & Otology , Volume 106 , Issue 7 , July 1992 , pp. 640 - 642
Copyright
Copyright © JLO (1984) Limited 1992

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