Hostname: page-component-848d4c4894-8kt4b Total loading time: 0 Render date: 2024-07-07T05:51:12.975Z Has data issue: false hasContentIssue false

Studies of Immunity to Fasciola hepatica: Acquired immunity in cattle, sheep and rabbits following natural infection and vaccine procedures

Published online by Cambridge University Press:  05 June 2009

J. G. Ross
Affiliation:
Veterinary Research Laboratories, Stormont, Belfast 4.Northern Ireland

Extract

Investigations of acquired immunity to Fasciola hepatica in calves, sheep and rabbits are described. With injections of extracts of imma- ture parasites retarded growth of the challenge infection was observed between the 6th and 7th week. Following a previous experience of a natural infection or viable fluke implants, retardation and reduced take of the challenge infection were observed. Considerable individual variation was present and the level of significance between treatment and control groups was low.

Type
Research Article
Copyright
Copyright © Cambridge University Press 1967

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Ershov, V. S., 1959.—“The problem of immunisation of domestic animals to helminthosis.” Proc. 16th Int. Vet. Congr. Madrid, 279.Google Scholar
Healy, G. R., 1955.—“Studies on immunity to Fasciola hepatica in rabbits.” J. Parasit., 41, 25.Google Scholar
Hughes, D. L.. 1962.—“Observations on the immunology of Fasciola hepatica infections in mice and rabbits.” Parasitology, 52, 4.Google Scholar
Hughes, D. L., 1903.—“Some studies on the host-parasite relations of Fasciola hepatica”. Ph.D., Thesis. University of London.Google Scholar
Kerr, K. B. and Pethovich, O. L., 1935.—“Active Immunity in rabbits to the liver fluke, Fasciola hepatica.” J. Parasit., 21, 319.CrossRefGoogle Scholar
Lang, B. Z., 1905.—“Fasciola hepatica in the laboratory white mouse.” J. Parasit., 51, 22.Google Scholar
Ross, J. G.,—1965a.—“Experimental infections of cattle with Fasciola hepatica: a s effect of level comparison of low and high infection rates.” Nature, Lond., 208, 907.CrossRefGoogle Scholar
Ross, J. G., 1905b.—“Infections of cattle with Fasciola hepatica. The effect of infection on the fate of the parasite.” Parasitology, 55, 1.Google Scholar
Ross, J. G., 1966a.—“Experimental infections of cattle with Fasciola hepatica. Challenge infections of previously infected calves and acquired self care.” Nature, Lond., 212, 1404.Google Scholar
Ross, J. G., 1966b.—“Studies of immunity to Fasciola hepatica. Naturally acquired immunity in rabbits.” Br. Vet. J., 122, 209.Google Scholar
Ross, J. G., Todd, j. R. and Dow, C., 1966.—“Single experimental infections of calves with the liver fluke Fasciola hepatica, (Linnaeus 1758).” J. comp. Path. Ther., 76, 67.Google Scholar
Shibanai, D., Towyawa, M., Takahaski, M., AND Isoda, M., 1950.—“Experimental studies on vaccination against Fasciola hepatica.” Bull. Azabu Vet. Coll., 3, 80.Google Scholar
Taylor, E. L., 1949.—“The epidemiology of fascioliasis in Britain.” Proc. 14th Int. Vet. Congr. London, 2, 81.Google Scholar
Thorpe, E. and Broome, A. W. J., 1902.—“Immunity to Fasciola hepatica infection in albino rats vaccinated with irradiated metacercariae.” Vet. Rec., 74, 755.Google Scholar
Urquhart, G. M., Mulligan, W. and Jennings, F. W., 1954.—“Artificial immunity to Fasciola hepatica in rabbits. 1. Some studies with protein antigens of F. hepatica.” J. inf. Dis., 94, 120.Google Scholar