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Strongyloides ratti: chemotactic responses of third-stage larvae to selected serum proteins and albumins

Published online by Cambridge University Press:  12 April 2024

M. Koga  and
I. Tada
M. Koga*
Affiliation:
Department of Parasitology, Faculty of Medicine, Kyushu University, Fukuoka 812–8582, Japan
I. Tada
Affiliation:
Department of Parasitology, Faculty of Medicine, Kyushu University, Fukuoka 812–8582, Japan
*
*Fax: +81 92 642 6115 E-mail: masakoga@linne.med.kyushu-u.ac.jp
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Abstract

Experiments were carried out in vitro to investigate whether the sera of several animals as well as albumins and peptides might act as attractants for larvae of Strongyloides ratti. Samples of sera from several mammal species were dialysed and the aliquots were further centrifuged using ultrafiltration cartridges to remove any remaining small molecules. Additional test substances included commercially obtained ovalbumin, rat and bovine serum albumins, polypeptides such as peptone, tryptone and tryptose, amino nitrogens, monosaccharides, and reduced glutathione (triaminopeptide). Larvae were strongly attracted to the dialysed mammalian sera, which mainly consisted of serum albumin and globulins. Ov- and serum albumins, and polypeptides also acted as attractants. On the other hand, reduced glutathione, 16 kinds of amino acids and four kinds of monosaccharides did not attract this nematode.

Type
Research Article
Information
Journal of Helminthology , Volume 74 , Issue 3 , September 2000 , pp. 247 - 252
Copyright
Copyright © Cambridge University Press 2000

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