Hostname: page-component-77c89778f8-fv566 Total loading time: 0 Render date: 2024-07-17T13:14:37.291Z Has data issue: false hasContentIssue false

Stage-specific immunogens of Hymenolepis nana in mice

Published online by Cambridge University Press:  05 June 2009

Akira Ito
Affiliation:
Department of Parastology, Gifu University School of Medicine, Tsukasa-Machi 40, Gifu 500, Japan

Abstract

Treatment with praziquantcl at the beginning of the lumen phase of Hymenolepis nana in mice showed conclusively that: (i) the mouse given eggs of H. nana produces two separate immune responses against reinfection, one directed exclusively against the tissue phase of egg challenge (early response), the other against the lumen phase of cysticcrcoid challenge (late response); (ii) a tissue phase of egg inoculation is not necessary for initiating the late response but is necessary to provoke the early response; and (iii) H. nana expresses several stage-specific immunogens through its development in the mouse host.

Type
Research Note
Copyright
Copyright © Cambridge University Press 1984

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

REFERENCES

Bailey, W.S. (1951) Host-tissue reactions to initial and superimposed infections with Hymenotepis nana var. fraterna. Journal of Parasitology, 37, 440444.CrossRefGoogle ScholarPubMed
Berntzen, A.K. & Voge, M. (1965) In vitro hatching of oncosphcrcs of four hymenolcpidid ecstodes. Journal of Parasitology, 51, 235242.CrossRefGoogle Scholar
Friedberg, W., Neas, B.R., Faulkner, D.N. & Congdon, C.C. (1979) Hymenolepis nana: intestinal tissue phase in actively immunized mice. Journal of Parasitology, 65, 6164.CrossRefGoogle ScholarPubMed
Hearin, J.T. (1941) Studies on the acquired immunity to the dwarf tapeworm Hymenolepis nana var. fraterna, in the mouse host. American Journal of Hygiene, 33, 7187.Google Scholar
Heath, D.D. & Pavloff, P. (1975) The fate of Taenia taeniaeformis oncospheres in normal and passively protected rats. International Journal for Parasitology, 5, 8388.CrossRefGoogle ScholarPubMed
Heyneman, D. (1962a) Studies on helminth immunity: IV. Rapid onset of resistance by the white mouse against a challenging infection with eggs of Hymenolepis nana (Cestoda: Hymenolepididae). Journal of Immunology, 88, 210220.Google ScholarPubMed
Heyneman, D. (1962b) Studies on helminth immunity: I. Comparison between lumenal and tissue phases of infection in the white mouse by Hymenolepis nana (Cestoda: Hymenolepididae). American Journal of Tropical Medicine and Hygiene, 11, 4663.CrossRefGoogle ScholarPubMed
Hunninen, A.V. (1935a) Studies on the life history and host-parasite relations of Hymenolepis fraterna (H. nana var. fraterna Stiles) in white mice. American Journal of Hygiene, 22, 414443.Google Scholar
Hunninen, A.V. (1935b) A method of demonstrating cysticercoids of Hymenolepis fraterna (H. nana var. fraterna Stiles) in the intestinal villi of mice. Journal of Parasitology, 21, 124125.CrossRefGoogle Scholar
Ito, A. (1977a) A simple method for collecting infective cysticercoids of Hymenolepis nana from the mouse intestine. Journal of Parasitology, 63, 167168.CrossRefGoogle ScholarPubMed
Ito, A. (1977b) The mode of passive protection against Hymenolepis nana induced by scrum transfer. International Journal for Parasitology, 7, 6771.CrossRefGoogle Scholar
Ito, A. (1978) Hymenolepis nana: Protective immunity against mouse-derived cysticercoids induced by initial inoculation with eggs. Experimental Parasitology, 46, 1219.CrossRefGoogle ScholarPubMed
Ito, A. (1980) Hymenolepis nana: Survival in the immunized mouse. Experimental Parasitology, 49,248257.CrossRefGoogle ScholarPubMed
Ito, A. (1981) Comparison of the kinetics of infection with Hymenolepis nana between BALB/c and dd strains of mice. Japanese Journal of Parasitology, 30, 439446.Google Scholar
Ito, A. (1982) Hymenolepis nana: Immunogcnicity of a lumen phase of the direct cycle and a failure of autoinfection in BALB/c mice. Experimental Parasitology, 54, 113120.CrossRefGoogle Scholar
Ito, A. & Yamamoto, M. (1976) The mode of active protection against Hymenolepis nana reinfection in mice inoculated with different doses of shell-free eggs. Japanese Journal of Parasitology, 25, 247253.Google Scholar
Ito, A., Yamamoto, M. & Okamoto, K. (1978) Primary infection with mouse-derived cysticercoids of Hymenolepis nana prepared from baby or adult mice and secondary infections with eggs or cysticercoids. International Journal for Parasitology, 8, 149153.Google ScholarPubMed
Kano, S. & Ito, A. (1983) Influence of the host immune responses on the modes of primary infection and autoinfection with Hymenolepis nana in mice. Japanese Journal of Parasitology, 32, 183193.Google Scholar
Marshall, I. (1982) The effects of sustained-release praziquantel on the survival of Hymenolepis nana in laboratory mice. Annals of Tropical Medicine and Parasitology, 75, 115116.CrossRefGoogle Scholar
Patton, S. (1977) Studies on the passive transfer via serum of immunity to Hymenolepis nana in the mouse Mus musculus. Transaction of the Kentucky Academy of Science, 38, 5661.Google Scholar
Rickard, M.D. (1982) Immunization against infection with larval Tacniid ecstodes using oncospheral antigens. In: Cysticercosis: Present state of knowledge and perspectives (editors, Flisser, A., Willms, K., Laclettc, J.P., Larralde, C., Ridaura, C. & Beltran, F.) pp. 633646. Academic Press: New York.Google Scholar
Rickard, M.D. & Williams, J.F. (1982) Hydatidosis/Cysticcrcosis: Immune mechanisms and immunization against infection. Advances in Parasitology, 21, 229296.CrossRefGoogle ScholarPubMed
Thomas, H. & Gönnert, R. (1977) The efficacy of praziquantel against cestodes in animals. Zeitschrift für Parasitenkunde, 52, 117127.CrossRefGoogle ScholarPubMed
Weinmann, C.J. (1974) Hymenolepis nana in mice: a potential model for the study of intestinal immunity. Proceedings of the Third International Congress of Parasitology, Munich, 589.Google Scholar
Williams, J.F. (1982) Cestode infections. In: Immunology of Parasitic Infections (2nd edition) (editors, , S.Cohen, & Warren, K.S.) pp. 676714. Blackwell Scientific Publications: Oxford.Google Scholar