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Cross-reactivity induced by Anisakis simplex and Toxocara canis in mice

Published online by Cambridge University Press:  12 April 2024

M.J. Perteguer
Affiliation:
Departamento de Parasitología, Facultad de Farmacia, Universidad Complutense, 28040 Madrid, Spain
C. Águila
Affiliation:
Sección de Biología Animal y Parasitología, Facultad de Ciencias Experimentales y de la Salud, Universidad San Pablo, Madrid, Spain
S. Fenoy
Affiliation:
Sección de Biología Animal y Parasitología, Facultad de Ciencias Experimentales y de la Salud, Universidad San Pablo, Madrid, Spain
J.L. Guillén*
Affiliation:
Departamento de Parasitología, Facultad de Farmacia, Universidad Complutense, 28040 Madrid, Spain
*
*Author for correspondence Fax: +34 91 394 1815 E-mail: cuellarh@farm.ucm.es

Abstract

The aim of this study was to verify whether cross-reactivity appeared between Toxocara canis and Anisakis simplex in an experimental rodent model. No cross-reactions were detected using sera from mice infected with T. canis eggs. When responses obtained against T. canis ES antigen using sera from BALB/c and C57BL/10 mice infected with T. canis eggs were compared with those obtained by testing sera from mice infected with one A. simplex L3, an increase in cross-reactions was observed using the C57BL/10 strain.

Type
Review Article
Copyright
Copyright © Cambridge University Press 2003

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