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Comparison of human and murine isolates of Schistosoma mansoni from Richard-Toll, Senegal, by isoelectric focusing

Published online by Cambridge University Press:  05 June 2009

M. Sène ,
P. Brémond ,
J.P. Hervé ,
V.R. Southgate ,
B. Sellin ,
B. Marchand  and
J.M. Duplantier
M. Sène
Affiliation:
Programme ‘Eau et Santé’, ORSTOM, B.P. 1386, Dakar, Sénégal: Departement de Biologic Animale, Faculté des Sciences, Université Cheikh Anta Diop de Dakar, Sénégal: Department of Zoology, The Natural History Museum, Cromwell Road, London, SW7 5BD, UK:
P. Brémond
Affiliation:
Programme RAMSE, ORSTOM, B.P. 434, Antananarivo 101, Madagascar:
J.P. Hervé
Affiliation:
ORSTOM, Montpellier B.P. 5045, 911 Avenue Agropolis, 34032 Montpellier Cedex, France:
V.R. Southgate
Affiliation:
Department of Zoology, The Natural History Museum, Cromwell Road, London, SW7 5BD, UK:
B. Sellin
Affiliation:
Programme RAMSE, ORSTOM, B.P. 434, Antananarivo 101, Madagascar:
B. Marchand
Affiliation:
Laboratoire Arago, Université Pierre et Marie Curie, CNRS URA 2156, B.P. 44, 66651 Banyuls-sur-Mer Cedex, France
J.M. Duplantier
Affiliation:
Programme RAMSE, ORSTOM, B.P. 434, Antananarivo 101, Madagascar:
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Abstract

Studies on human and murine isolates of Schistosoma mansoni, from Richard-Toll, Senegal, were carried out by isoelectric focusing in polyacrylamide gels. Seven enzyme systems; lactate dehydrogenase (LDH), malate dehydrogenase (MDH), glucose-6-phosphate dehydrogenase (G6PD), acid phosphatase (AcP), hexokinase (HK), glucose phosphate isomerase (GPI), and phosphoglucomutase (PGM), were used to compare the two isolates. All systems tested, apart from LDH, were found to be polymorphic for both isolates. Interestingly, one phenotype is more frequent than the remainder. The results show that there is no significant genetic variation between the S. mansoni isolates from man and the rodents, Arvicanthis niloticus and Mastomys huberti.

Type
Research Papers
Information
Journal of Helminthology , Volume 71 , Issue 2 , June 1997 , pp. 175 - 181
Copyright
Copyright © Cambridge University Press 1997

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