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The comparative efficacy of oxfendazole administered as bolus and suspension to naturally infected sheep in Greece

Published online by Cambridge University Press:  05 June 2009

C. A. Himonas  and
J. Theodorides
C. A. Himonas
Affiliation:
Department of Infectious and Parasitic Diseases, Avian Medicine and Pathology, Faculty of Veterinary Medicine, Aristotelian University, Thessaloniki 54006 Greece
J. Theodorides
Affiliation:
Department of Infectious and Parasitic Diseases, Avian Medicine and Pathology, Faculty of Veterinary Medicine, Aristotelian University, Thessaloniki 54006 Greece
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Abstract

In a flock of 20 ewes naturally infected with those parasites of sheep most common in Greece, and kept indoors during the whole trial, oxfendazole at the dose rate of approximately 2–9 and 2–8 mg/kg body-weight was tested as a 4 g bolus containing 112 mg active ingredient and a 2–265% suspension. The evaluation of its efficacy was based on the necropsy findings which were also supported by faecal egg counts. No differences in efficacy were noticed between the two formulations of the drug. Both bolus and suspension proved to be 100% effective against Haemonchus contortus, Ostertagia circumcincta, Trichostrongylus axei, T. colubriformis and Chabertia ovina. The efficacy against Cooperia oncophora, Nematodirus spathiger, Bunostomum trigonocephalum, Oesophagostomum columbianum and Moniezia expansa could not be evaluated, because these species, though not found in any of the treated animals, were found in fewer than three controls.

Keywords

oxfendazolesheepGreeceHaemonchus contortusOstertagia circumcinctaTrichostrongylus axeiTrichostrongylus colubriformisChabertia ovina
Type
Research Article
Information
Journal of Helminthology , Volume 60 , Issue 3 , September 1986 , pp. 245 - 249
Copyright
Copyright © Cambridge University Press 1986

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References

REFERENCES

Baker, N. F. & Fisk, R. A (1977) Anthelmintic efficacy of oxfendazole in California lambs. American Journal of Veterinary Research, 38, 1315–1316.Google Scholar
Berger, J. (1980) Oxfendazole: Anthelmintic activity in sheep artificially infected with nematodes. Results of trials against nine species including benzimidazole resistant Haemonchus contortus. Journal of the South African Veterinary Association, 51, 51–58.Google ScholarPubMed
Borgsteede, F. H. M., Van Den Burg, W. P. J. & Reid, J. F. S. (1981) The efficacy of oxfendazole administered as a bolus compared with a drench formulation. Veterinary Quarterly, 3, 101–103.CrossRefGoogle ScholarPubMed
Chalmers, K. (1977) The efficacy of oxfendazole against natural infections of nematodes in sheep. New Zealand Veterinary Journal, 25, 266–269.CrossRefGoogle ScholarPubMed
Chalmers, K. (1979) The efficacy of oxfendazole against naturally acquired Dictyocaulus spp. in sheep and cattle. New Zealand Veterinary Journal, 27, pp. 8 & 13.CrossRefGoogle ScholarPubMed
Downey, N. E. (1977) Controlled trials of the anthelmintic oxfendazole in ewes and lambs naturally infected with gastrointestinal nematodes. Veterinary Record, 101, 260–263.Google Scholar
Furmaga, S., Gundlach, J. L., Sadzikowski, A. & Paciejewski, S.P. (1982) Systamex (oxfendazole) in the treatment of parasites of sheep. Medycyna Weterynaryjna, 38, 269–271.Google Scholar
Kistner, T. P., Wyse, D., Schiltz, R. A., Averkin, E. & Cary, A. (1979) A dose titration study with oxfendazole against naturally acquired helminths in sheep. Veterinary Parasitology, 5, 195–204.Google Scholar
Lafranchi, R. S., Reid, J. F. S. & Montellini, A.C. (1980) The anthelminitic activity of oxfendazole in sheep and cattle in Northern Italy. Annali della Facolta di Medicina Veterinaria di Torino, 27, 1–14.Google Scholar
Leimbacher, F., Nicolas, J. A. & Delahaye, J. (1976) Experimentation, dans les condition d'élevage de l'oxfendazole, un nouvel anthelminthique pour lutte contre less “strongyloses” gastro-intestinales des agneaux a 1'herbe. Revue de Midecine Veterinaire, 127, 941–952, 955–958.Google Scholar
Le Jambre, L. F., Prichard, P. K., Hennessy, D. R. & Laby, R. H. (1981) Efficiency of oxfendazole administered as a single dose or in a controlled release capsule against benzimidazole-resistant Haemonchus contortus, Ostertagia circumcincta and Trichostrongylus colubriformis. Research in Veterinary Science, 31, 289–294.CrossRefGoogle ScholarPubMed
M.A.F.F (1977) Manual of Veterinary Parasitological Laboratory Techniques, 2nd edit.HMSO, Technical Bulletin No 18.Google Scholar
Michael, S. A., El Refall, A. H., Mansour, W. H., Selim, M. K. & Higgins, A. J. (1979) Efficacy of oxfendazole against natural infections of nematodes and cestodes in sheep in Egypt. Veterinary Record, 104, 338–340.CrossRefGoogle ScholarPubMed
Niec, R., Lukovich, R., Eddi, C., Nunez, J., Moltedo, H. L. & Manos Cobanas, M. E. (1980) Accion antihelmintica del Oxfendazole en ovinos a dosis de 2–5 mg/kg; 3–5 mg/kg y 4–5 mg/kg. Revista de Medecina Veterinaria, 61, 249–252.Google Scholar
Ogunsusi, R. A. (1979) The anthelmintic efficacy of oxfendazole and haloxon against arrested Haemonchus contortus larvae in sheep. Research in Veterinary Science, 27, 131–132.CrossRefGoogle ScholarPubMed
Reuss, U. (1979) Behandlungsversuche des Magendarm- und Bandwurmbefalls der Schafe mit dem Breitbanthelminthicum “Synanthic” unter tierarztlichen Praxisbedingungen. Tierärztliche Umschau, 34, 836–842.Google Scholar
Skrjabin, K. I. (1952) Key to Parasitic Nematodes. Vol. 111. Strongylata. Israel Program for Scientific Translations 1961.Google Scholar
Skrjabin, K. I. (1954) Essentials of Nematodology. Vol. III. Trichostrongylids of Animals and Man. Israel Program for Scientific Translations 1960.Google Scholar
Thomas, R. J. & Reid, J.F. S. (1980) Efficacy of oxfendazole against Nematodirus battus and inhibited stages in sheep nematodes. Research in Veterinary Science, 28, 134–136.CrossRefGoogle ScholarPubMed
Todd, K. S. & Mansfield, M.E. (1979) Evaluation of four forms of oxfendazole against nematodes of cattle. American Journal of Veterinary Research, 40, 423–424.Google ScholarPubMed
Westcott, R. B., Shelton, T. A. & Gates, N.C. (1979) Anthelmintic efficacy of oxfendazole in sheep. Western Veterinarian, 17, 22–23Google Scholar
YazwNski, T.A. & Bess, C. (1980) Levels of helminthiasis and the efficacy of oxfendazole on three Arkansas sheep farms. Veterinary Medicine and Small Animal Clinician, 75, 310–314.Google Scholar