Periconception nutrition and long term impacts S1

Could the intestinal microbiota be programmed by early life environment? S1

Epigenetic and animal reproduction, tools and challenges S2

Preterm birth and intraruterine growth restriction (IUGR): from perinatal period to long term consequences at adulthood S2

How to feed preterm infants to limit unfavorable long-term outcome? S3

Programmation, methyl donors, epigenetics S4

Exposure to early life stress: mechanisms of system wide epigenetic effects S5

Early risk factors for childhood cancer S5

Determinants of the atopic march S6

Early life adversity, environmental enrichment, and long-term health S6

Transgenerational inheritance of diabetes risk by early paternal malnutrition S7

A short periconceptional maternal hyperglycemia is sufficient to disrupt the feto-placental phenotype in a rabbit model S7

Maternal weight status prior and during pregnancy and offspring’s adiposity at 5 to 6 years of age in the EDEN mother–child cohort S8

Effects of maternal preconception weight trajectory on offspring health S9

A mice model of preconceptional maternal weight loss S9

Long-term modulation of gut mast cell- and tryptase-mediated gut permeability alterations by neonatal probiotic Lactobacillus amylovorus administration and late high fat diet in pig offspring born to peripartum antibiotic-treated mothers S10

Long-term modulation of gut inducible heat shock proteins and resistance to oxidative stress by neonatal probiotic Lactobacillus amylovorus administration and late high fat diet in pig offspring born to peripartum antibiotic-treated mothers S11

Neonatal microbiota diversity and structure modulate further resistance to post-weaning diarrhea in pigs S12

Chronic stress triggers sex-specific divergent trajectories of gene expression in mouse adipose depots. S12

Does early oligosaccharides consumption affect pancreas maturation? S13

Prevention of gut leakiness in pups exposed to chronic maternal separation prevents long-term emotional disturbances in adulthood. S13

Placenta and endometrium imprinting related of piglet maturity S14

Excess of methyl donors in maternal diet affects postnatal down regulation of Igf2, Igf2r and H19 genes in liver S15

RNA-mediated paternal heredity of diet-induced obesity and diabetes S15

Research of microRNA biomarkers of gestational diabetes in bloods of umbilical cords S16

Genome-wide analysis of DNA methylation and gene expression in liver in response to maternal protein-restriction or methyl donor deficiency reveal a set of genes that might drive the nutritional programming of metabolic disorders irrespective of the nutritional insult. S16

Impact on epigenetic machinery genes expression and on foeto-placental development of preconceptional maternal weight loss S17

Placental contribution to nutritional programming of health and diseases: ontogenesis epigenetics and sexual dimorphism S18

Epigenetic basis for adaptive phenotype in the human parasite Schistosoma mansoni S18

Synchronization capacity of fibroblast primary cultures established from mother and first generation offspring in a model of protein restriction. S19

Rats born with intrauterine growth retardation are resistant to cholecystokinin-induced inhibition of food intake. S19

Maternal exposure to diesel exhaust during pregnancy affects postnatal health of the offspring, in a rabbit model S20

Anabolic effect of citrulline and arginine in a model of intrauterine growth restriction (IUGR): role of hormones and placental amino acid transporters S21

The complex relationships of birth weight and early growth on blood pressure at 5 years: overcoming the reversal paradox in the EDEN cohort S22

Is there a negative direct effect of birth weight on blood pressure? A causal mediation analyses S22

SGA Children with Moderate Catch-Up Growth Are Showing Impaired Insulin Secretion at the Age of 4 S23

UCP 1 is present in porcine adipose tissue and is responsive to postnatal leptin S23

Developmental programming of hypertension in IUGR rat model: implication of arginase pathway and eNOS uncoupling S24

Modulation of oxidative stress via SIRT1 expression: a role in the developmental programming of endothelial dysfunction in preterm infants S25

Is high fat diet-induced hypothalamic plasticity modified by intrauterine growth restriction? S25

Preterm delivery and low fœtal birth weight: Preliminary result at hôpital Privé Natecia (Lyon) S26

Intrauterine growth restriction is associated to altered expression patterns of sirtuins and key metabolic genes in pig skeletal muscle. S26

Exercise before and during an obese mouse pregnancy restores some placental gene expression and transport function S27

Perinatal protein restriction effect on maternal milk composition throughout the lactation period and its potential role on metabolic trajectories of the offspring and their outcome at adulthood. S27

Formula Milk is involved in programming of oxidative stress and inflammation in kidney of IUGR piglets S28

Risk Factors for Overweight and Obesity in 8-9 Years Old Children in the District of Constantine (Algeria) S29

Breast-Feeding and Adult Body Fat: the Missing Confounding Factor S29

Barley supplementation at mid-gestation in broodmares does not affect fetal development and is accompanied with minimal placental adaptations S30

Early nutrition: transcriptomic profiling of exfoliated cells, microvesicles and exosomes from breast milk and corresponding gastric fluid aspirate of preterm infant. S31

Adherence to French nutritional guidelines among pregnant women from the Elfe survey S31

Maternal nutrition during lactation dictates milk composition and has long-term metabolic consequences in the male rat offspring S32

Females from undernourished mothers are predisposed to altered placental function and offspring growth when fed a high-fat diet before and/or during gestation. S32

Maternal obesity predisposes adult male rat offspring to increased adiposity through induction of lipogenic genes S33

Consequences of early nutrition on the developing sweet/fatty taste, eating behaviour and motivation for palatable foods in the rodent model, from birth to sexual maturity S33

Socio-cultural determinants on breastfeeding initiation and duration in France: Preliminary results from the Elfe study S34

Maternal high fat diet prevents the decrease in basilar spine density in the medial prefrontal cortex of pups exposed to chronic maternal separation S35

Impact of chronic maternal separation on emotion and motivation for food reward in C57BL6/J and C3H/Hen mice S35

Comparison between exogenous and endogenous miRNAs as standards for appropriate normalization of microRNAs quantitative PCR analysis in breast milk to assess their potential role in nutritional programming S36

Cytotoxic effect of low doses of a maternal food contaminants mixture on pancreatic cells S37

Plasma apelin variations during pregnancy in obese mice: role of the placenta. S37

Dietary scFOS supplementation during prenatal and early postnatal life influences metabolic and immunologic responses in adults fed a high-fat diet S38

High protein diet exposure during gestation but not during lactation modifies female rat pups response to dietary challenge in adulthood S39

Is perinatal butyrate intake, through maternal supplementation, able to prevent cognitive impairment due to intrauterine growth restriction in a rat model? S39

High-fat high-sugar maternal diet has consequences on milk composition and offspring’s microbiota activity, metabolism and behavioural responses in Yucatan pigs. S40

Effects of in utero exposure to pesticides on foetal development in the Picardie region of France: use of meconium in the MecoExpo cohort. S40

Predictive factors for hypospadias in the Picardie region of France: a preliminary study. S41

The determinants of child health in district of Constantine (Algeria) S42

Consequences of perinatal exposure to a pesticide, alone or combined with a prebiotic: effects on energy metabolism and microbiota composition. S42

Maternal smoking during pregnancy and offspring’s postnatal body mass index (BMI) trajectory between birth and five years from the EDEN mother child cohort study S43

Maternal exposure to diesel engine exhaust during pregnancy affects fetal and placental growth: validation of a rabbit model S43

Maternal gestational diabetes exposure and higher birth weight: Effects on offspring adiposity at 7 years S44

Moderate maternal diabetes in a rat’s model of fetal programming involves modifications of mesenteric arteries reactivity in adult offspring S45

Specific associations of maternal and paternal obesity risk-allele scores with offspring early growth. S45

Placental prolactin family levels are modified during gestation in the diabetic rat S46

Night sleep trajectories and associated factors among the preschool children of the EDEN cohort S46

Longitudinal sleep study among French pregnant women and the impact on birth term and birth weight S47

The probiotics Lactobacillus reuteri DSM 17938 and Bifidobacterium longum ATCC BAA-999 normalize sleep disturbances in prenatally stressed rats S47

A modelling approach of the developmental origin of type 2 diabetes through the modulation of the beta cell mass. S48

Maternal protein-restriction induces selective changes in tryptophan metabolism in the brain embryo which are apposite to those observed in adult animals born to and nursed by protein-restricted dams S49

Methyl donor deficiency during gestation and lactation produces hepatosteatosis and myocardium fibrosis in rat offspring fed a high-fat diet in adult life S49