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The prevalence of coagulase-negative staphylococcus associated with bovine mastitis in China and its antimicrobial resistance rate: a meta-analysis

Published online by Cambridge University Press:  29 June 2023

Jianming Deng ,
Kai Liu ,
Kuan Wang ,
Bowen Yang ,
Hui Xu ,
Juyu Wang ,
Feiyan Dai ,
Xiao Xiao ,
Xiaolong Gu  and
Limei Zhang
...Show all authors
Jianming Deng
Affiliation:
College of Veterinary Medicine, Yunnan Agricultural University, Kunming, Yunnan Province 650201, PR China
Kai Liu
Affiliation:
College of Veterinary Medicine, Yunnan Agricultural University, Kunming, Yunnan Province 650201, PR China
Kuan Wang
Affiliation:
College of Veterinary Medicine, Yunnan Agricultural University, Kunming, Yunnan Province 650201, PR China
Bowen Yang
Affiliation:
College of Veterinary Medicine, Yunnan Agricultural University, Kunming, Yunnan Province 650201, PR China
Hui Xu
Affiliation:
College of Veterinary Medicine, Yunnan Agricultural University, Kunming, Yunnan Province 650201, PR China
Juyu Wang
Affiliation:
College of Veterinary Medicine, Yunnan Agricultural University, Kunming, Yunnan Province 650201, PR China
Feiyan Dai
Affiliation:
College of Veterinary Medicine, Yunnan Agricultural University, Kunming, Yunnan Province 650201, PR China
Xiao Xiao
Affiliation:
College of Veterinary Medicine, Yunnan Agricultural University, Kunming, Yunnan Province 650201, PR China
Xiaolong Gu
Affiliation:
College of Veterinary Medicine, Yunnan Agricultural University, Kunming, Yunnan Province 650201, PR China
Limei Zhang
Affiliation:
College of Veterinary Medicine, Yunnan Agricultural University, Kunming, Yunnan Province 650201, PR China
Weijie Qu*
Affiliation:
College of Veterinary Medicine, Yunnan Agricultural University, Kunming, Yunnan Province 650201, PR China
*
Corresponding author: Weijie Qu; Email: 1401075010@qq.com
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Abstract

To contribute to the treatment decision and optimize coagulase-negative staphylococcus (CNS) control programs, we conducted a meta-analysis to investigate the epidemiology and antimicrobial resistance rates of coagulase-negative staphylococcus associated with bovine mastitis in China. Three databases (PubMed, Google scholar and China National Knowledge Infrastructure database) were utilized to obtain relevant publications. A total of 18 publications were included in our research, and 3 of them included antimicrobial resistant (AMR) test. The pooled prevalence of coagulase-negative staphylococcus was 17.28%. Subgroup analysis revealed that the prevalence was higher in South China than in North China, was higher in 2011–2020 than in 2000–2010 and was higher in clinical bovine mastitis cases than in subclinical cases. The pooled AMR were most resistant to β-lactams, followed by tetracyclines, quinolones, nitrofurans, lincosamides, sulfonamides, amphenicol and aminoglycosides. The pooled AMR rate of coagulase-negative staphylococcus was lower in 2011–2020 than in 2000–2010. Although the prevalence of CNS showed an increasing trend over 20 years, the AMR rate showed a decreasing trend, and the clinical type of mastitis was the most frequent and the prevalence was highest in South China. Finally, CNS was most resistant to β-lactams amongst the eight groups of antimicrobial agents.

Keywords

Antimicrobials resistantbovine mastitiscoagulase negative staphylococcusmeta-analysisprevalence
Type
Research Article
Information
Journal of Dairy Research , Volume 90 , Issue 2 , May 2023 , pp. 158 - 163
Copyright
Copyright © The Author(s), 2023. Published by Cambridge University Press on behalf of Hannah Dairy Research Foundation

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Footnotes

*

These authors contributed equally.

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