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Inhibitory effect of dairy products on the mutagenicities of chemicals and dietary mutagens

Published online by Cambridge University Press:  01 June 2009

Pierrette Cassand ,
Hasnaa Abdelali ,
Christine Bouley ,
Gerard Denariaz  and
Jean F. Narbonne
Pierrette Cassand
Affiliation:
Laboratoire de Toxicologie Alimentaire, Université de Bordeaux I, 33405 Talence Cédex, France
Hasnaa Abdelali
Affiliation:
Laboratoire de Toxicologie Alimentaire, Université de Bordeaux I, 33405 Talence Cédex, France
Christine Bouley
Affiliation:
BSN, Centre International de Recherche Daniel Carrasso, 92350 le Plessis-Robinson, France
Gerard Denariaz
Affiliation:
BSN, Centre International de Recherche Daniel Carrasso, 92350 le Plessis-Robinson, France
Jean F. Narbonne
Affiliation:
Laboratoire de Toxicologie Alimentaire, Université de Bordeaux I, 33405 Talence Cédex, France
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Summary

The antimutagenic effects of uninoculated milk and milks cultured with Bifidobacterium or Lactobacillus strains towards the mutagenicity induced by two direct mutagens, 4-nitroquinoline N-oxide and 2-nitrofluorene, and three dietary indirect mutagens, aflatoxin B1, benzo(a)pyrene and quercetin, were investigated using the in vitro Salmonella typhimurium test. Each cultured milk sample and control milk had a significant antimutagenic effect, to an extent varying with the mutagen used. Uninoculated milk had a greater inhibitory effect than cultured milks towards dietary indirect mutagens.

Type
Original articles
Information
Journal of Dairy Research , Volume 61 , Issue 4 , November 1994 , pp. 545 - 552
Copyright
Copyright © Proprietors of Journal of Dairy Research 1994

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References

REFERENCES

Clemmensen, J. 1989 Antitumor effect of Lactobacilli substances: “L. bulgaricus effect”. Molecular Biotherapy 1 279–282Google Scholar
Fernandes, C. F. & Shahani, K. M. 1990 Anticarcinogenic and immunological properties of dietary lactobacilli. Journal of Food Protection 53 704–710CrossRefGoogle ScholarPubMed
Friend, B. A. & Shahani, K. M. 1984 Antitumor properties of lactobacilli and dairy products fermented by lactobacilli. Journal of Food Protection 47 717–723CrossRefGoogle ScholarPubMed
Goldin, B. R. 1989 Lactic Acid Bacteria: Implications for Health, pp. 95–104. Paris: John Libbey EurotextGoogle Scholar
Hosoda, M., Hashimoto, H., Morita, H., Chiba, M. & Hosono, A. 1992 Antimutagenicity of milk cultured with lactic acid bacteria against N-methyl-N′-nitro-N-nitrosoguanidine. Journal of Dairy Science 75 976–981CrossRefGoogle ScholarPubMed
Hosono, A., Kashina, T. & Kada, T. 1986 a Antimutagenic properties of lactic acid-cultured milk on chemical and fecal mutagens. Journal of Dairy Science 69 2237–2242CrossRefGoogle ScholarPubMed
Hosono, A., Sagae, S. & Tokita, F. 1986 b Desmutagenic effect of cultured milk on chemically induced mutagenesis in Escherichia coli B/r WP2 trp− hcr−. Milchwissenschaft 41 142–145Google Scholar
Hosono, A., Shashikanth, K. N. & Otani, H. 1988 a Antimutagenic activity of whole casein on the pepper-induced mutagenicity to streptomycin-dependent strain SD 510 of Salmonella typhimurium TA98. Journal of Dairy Research 55 435–442CrossRefGoogle Scholar
Hosono, A., Tanabe, T. & Otani, H. 1990 b Binding properties of lactic acid bacteria isolated from kefir milk with mutagenic amino acid pyrolyzates. Milchwissenschaft 45 647–651Google Scholar
Hosono, A., Wardojo, R. & Otani, H. 1990 a Inhibitory effects of lactic acid bacteria from fermented milk on the mutagenicities of volatile nitrosamines. Agricultural and Biological Chemistry 54 1639–1643CrossRefGoogle Scholar
Hosono, A., Yoshimura, A. & Otani, H. 1987 Antimutagenic activity of cellular component of Streptococcus faecalis IFO 12965. Netherlands Milk and Dairy Journal 41 239–245Google Scholar
Hosono, A., Yoshimura, A. & Otani, H. 1988 b Desmutagenic property of cell walls of Streptococcus faecalis on the mutagenicities induced by amino acid pyrolysates. Milchwissenschaft 43 168–170Google Scholar
Lowry, O. H., Rosebrough, N. J., Farr, A. L. & Randall, R. J. 1951 Protein measurement with the Folin phenol reagent. Journal of Biological Chemistry 193 265–275CrossRefGoogle ScholarPubMed
Maron, D. & Ames, B. N. 1983 Revised methods for the Salmonella mutagenicity test. Mutation Research 113 173–215CrossRefGoogle ScholarPubMed
Newmark, H. L. & Lipkin, M. 1992 Calcium, vitamin D, and colon cancer. Cancer Research 52 (Suppl.) 2067s–2070sGoogle Scholar
Reddy, G. V., Friend, B. A., Shahani, K. M. & Farmer, R. E. 1983 Antitumor activity of yogurt components. Journal of Food Protection 46 8–11CrossRefGoogle ScholarPubMed
Renner, H. W. & Munzner, R. 1991 The possible role of probiotics as dietary antimutagcns. Mutation Research 262 239–245Google Scholar
Schwartz, D. 1963 [Statistical Methods for Medical Men and Biologists.] 3rd edn, pp. 142–162. Paris: FlammarionGoogle Scholar
Zeiger, E. 1987 Carcinogenicity of mutagens: predictive capability of the Salmonella mutagenesis assay for rodent Careinogenicity. Cancer Research 47 1287–1296Google Scholar