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Induction of lambing: comparison of the effects of prostaglandin, oestradiol benzoate and dexamethasone

Published online by Cambridge University Press:  27 March 2009

M. P. Boland ,
T. F. Crosby  and
I. Gordon
M. P. Boland
Affiliation:
Department of Agriculture, University College, Lyons Estate, Newcastle, Co. Dublin, Eire
T. F. Crosby
Affiliation:
Department of Agriculture, University College, Lyons Estate, Newcastle, Co. Dublin, Eire
I. Gordon
Affiliation:
Department of Agriculture, University College, Lyons Estate, Newcastle, Co. Dublin, Eire
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Summary

In the first of two experiments 45 ewes were treated on day 141 of gestation with either prostaglandin F2a or saline. Doses of 10, 15, 20 or 25 mg PGF2a failed to induce lambing earlier than in control animals. A further 50 ewes were similarly treated on day 144; neither dose level of PGF2a nor day of administration had any effect on the interval from injection to lambing compared with controls. In a second experiment 159 ewes were randomly assigned to one of four treatment groups as follows: (1) 20 mg oestradiol benzoate (ODB); (2) 16 mg dexamethasone; (3) 15 mg PGF2a; (4) 2 ml saline. Ewes were injected on either day 143 or 144 of gestation and on each of those days animals were injected either in the morning or evening. The mean times to induction of lambing were 38·6 ± 20·8; 44·2 ± 18·1; 83·5 ± 39·8 and 82·9 ± 43·1 h for the four treatments respectively. Neither day nor time of treatment had any significant effect on the interval to lambing. Both ODB and dexamethasone induced parturition earlier than PGF2a or saline (P < 005).

Type
Research Article
Information
The Journal of Agricultural Science , Volume 98 , Issue 2 , April 1982 , pp. 391 - 394
Copyright
Copyright © Cambridge University Press 1982

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References

REFERENCES

Amir, D., Genizi, A. & Schindler, H. (1980). Seasonal and other changes in the gestation duration of sheep. Journal of Agricultural Science, Cambridge 95, 47–49.CrossRefGoogle Scholar
Ash, R. W. & Heap, R. B. (1973). The induction and synchronization of parturition in sows treated with I.C.I. 79,939, an analogue of prostaglandin F2a. Journal of Agricultural Science, Cambridge 81, 365–368.CrossRefGoogle Scholar
Boland, M. P., Craig, J. & Kelleher, D. L. (1979). Induction of farrowing: comparison of the effects of prostaglandin F2a (Lutalyse) and an analogue (Cloprostenol). Irish Veterinary Journal 33, 45–47.Google Scholar
Boland, M. P. & Gordon, I. (1979). Effect of timing of ram introduction on fertility in progestagen-PMSG treated anoestrous ewes. Journal of Agricultural Science, Cambridge 92, 247–249.CrossRefGoogle Scholar
Boland, M. P., Lemainque, F. & Gordon, I. (1978). Comparison of lambing outcome in ewes after synchronization of oestrus by progestagen or prostaglandin treatment. Journal of Agricultural Science, Cambridge 91, 765–766.CrossRefGoogle Scholar
Bosc, M. J. (1972). The induction and synchronization of lambing with the aid of dexamethasone. Journal of Reproduction and Fertility 28, 347–357.CrossRefGoogle ScholarPubMed
Cahill, L. P., Knee, B. W. & Lawson, R. A. S. (1976). Induction of parturition in ewes with a single injection of oestradiol benzoate. Theriogenology 5, 289–294.CrossRefGoogle Scholar
Challis, J. R. G. (1971). Sharp increase in free circulating cestrogens immediately before parturition in sheep. Nature, London 229, 208.CrossRefGoogle Scholar
Challis, J. R. G., Harrison, F. A. & Heap, R. B. (1971). Uterine production of oestrogens and progesterone at parturition in sheep. Journal of Reproduction and Fertility 25, 306–307.CrossRefGoogle Scholar
Day, A. M. & Southwell, S. R. G. (1979). Termination of pregnancy in goats using cloprostenol. New Zealand Veterinary Journal 27, 207–208.CrossRefGoogle ScholarPubMed
Emadi, M. & Noakes, D. E. (1973). The pharmacological control of the time of parturition in the ewe. Veterinary Record 93, 76.CrossRefGoogle ScholarPubMed
Emadi, M., Noakes, D. E., Hadley, J. C. & Arthur, G. H. (1974). Corticosteroid induced lambing in the ewe. Veterinary Record 95, 281–285.CrossRefGoogle Scholar
Haresign, W. & Webster, G. M. (1981). The induction of parturition in ewes with dexamethasone. Animal Production 32, 371 (Abstract).Google Scholar
Harman, E. L. & Slyter, A. L. (1980). Induction of parturition in the ewe. Journal of Animal Science 50, 391–393.CrossRefGoogle ScholarPubMed
Joyce, M. J. B. (1974). The use of dexamethasone to induce parturition in ewes synchronized for oestrus. Irish Veterinary Journal 28, 127–131.Google Scholar
Lucas, J. M. S. & Notman, A. (1974). The use of corticosteroids to synchronize parturition in sheep. British Veterinary Journal 130, i–v.CrossRefGoogle ScholarPubMed
Lynch, P. B. & Langley, O. H. (1977). Induced parturition in sows using prostaglandin analogue (I.C.I. 80,996). Irish Journal of Agricultural Research 16, 259–265.Google Scholar
Nancarrow, C. D., Hearnshaw, H., Mattner, P. E., Connell, P. J. & Restall, B. J. (1974). Hormonal changes occurring in cattle following the administration of prostaglandin F2a. Journal of Reproduction and Fertility 36, 484–485.CrossRefGoogle Scholar
Obst, J. M. & Seamark, R. F. (1972). Plasma oestrogen concentrations in ewes during parturition. Journal of Reproduction and Fertility 28, 161–162.CrossRefGoogle ScholarPubMed
Robinson, T. J. (1980). Programmed year-round sheep breeding. Australian Journal of Experimental Agriculture and Animal Husbandry 20, 667–673.CrossRefGoogle Scholar
Shevah, Y. (1974). A note on the use of dexamethasone for inducement of parturition of Finn x Dorset ewes. Animal Production 18, 89–92.Google Scholar
Thorburn, G. D. (1979). Physiology and control of parturition: reflections on the past and ideas for the future. Animal Reproduction Science 2, 1–27.CrossRefGoogle Scholar
Walker, N. (1977). The effects of induction of parturition in sows using an analogue of prostaglandin F2a. Journal of Agricultural Science, Cambridge 89, 267–271.CrossRefGoogle Scholar