Skip to main content Accessibility help
×
Home

Serum immunoglobulins in tardive dyskinesia — implication for pathogenesis of the syndrome

  • Hanafy Youssef (a1)

Abstract

Levels of immunoglobulins were measured in 32 schizophrenic patients with tardive dyskinesia and 34 schizophrenic patients without tardive dyskinesia. The duration of neuroleptic treatment in years was similar in the two groups. The serum immunoglobulin concentrations (mg%) were found to be significantly different in the two groups; IGA and IGM levels were higher in patients with tardive dyskinesia. The present results may be explained on the basis of dysfunction of the immunological system in tardive dyskinesia.

Copyright

References

Hide All
1.Youssef, HA, Waddington, JL. Primitive (developmental) reflexes and diffuse cerebral dysfunction in schizophrenia and bipolar affective disorder: over representation in patients with tardive dyskinesia. Biol Psychiatry 1988; 23: 791796.
2.Waddington, JL, Youssef, HA. An unusual cluster of tardive dyskinesia in schizophrenia: association with cognitive dysfunction, and negative symptoms. Am J Psychiatry 1986; 143: 11621165.
3.De Keyser, J, Ebinger, G, Herrgods, P. Pathophysiology of akathisia. Lancet 1987; ii: 336.
4.Mukherjee, S, Wisniewski, A, Bilder, R, Sackheim, HA. Possible association between tardive dyskinesia and altered carbohydrate metabolism. Arch Gen Psychiatry 1985; 42: 205.
5.Youssef, HA, Waddington, JL. Calcium metabolism and abnormal involuntary movements, (tardive dyskinesia) in psychosis. Acta Psychiatr Scand 1988; 78: 523525.
6.Tarsy, D. History and definition of tardive dyskinesia. Clin Neuropharmacol 1983; 6: 9199.
7.Feighner, JP, Robins, E, Guze, SB, Woodruff, RA Jr, Winokur, G, Munoz, R. Diagnostic criteria for use in psychiatric research. Arch Gen Psychiatry 1972; 26: 5763.
8.National Institute of Mental Health. Abnormal involuntary movement scale. In: Guy, W, ed. ECDEU assessment manual. Rockville: US Department of Health, Education and Welfare, 1976: 534537.
9.Bock, E, Weeke, B, Rafaelsen, O. Serum protein in acutely psychotic patients. J Psychiatr Res 1971; 9: 19.
10.Fessel, W. Blood protein in functional psychosis. Arch Gen Psychiatry 1962; 6: 132144.
11.Libikova, H. Schizophrenia and viruses: principles of etiologic studies. In: Adv Biolog Psych. Basel: Karger, 1983; 12: 2051.
12.Solomon, G, Allansmith, M, McCellan, B, Amkraut, A. Immunoglobulin in psychiatric patients. Arch Gen Psychiatry 1969; 20: 272277.
13.Shaskan, E, Lovett, E. Effects of psychotropic drugs on delayed type hypersensitivity reaction in mice: relevant sites of action. In: Perris, , Strune, , Jansson, . Biological Psychiatry. Amsterdam: Elsevier, 1981: 7384.
14.Kane, J, Smith, J. Tardive dyskinesia: prevalence and risk factor, 1959 - 1979. Arch Gen Psychiatry 1982; 36: 473481.
15.Waddington, JL, Youssef, HA, Molloy, AG, O'Boyle, KM, Pugh, MT. Association of intellectual impairment, negative symptoms, and ageing with tardive dyskinesia: clinical and animal studies. J Clin Psychiatry 1985; 46: 2933.
16.Struve, F, Wilner, A. Cognitive dysfunction and tardive dyskinesia. Br J Psychiatry 1983; 143: 597600.
17.Youssef, H, Waddington, J. Morbidity and mortality in tardive dyskinesia association in chronic schizophrenia. Acta Psychiatr Scand 1987; 75: 7477.

Keywords

Metrics

Full text views

Total number of HTML views: 0
Total number of PDF views: 0 *
Loading metrics...

Abstract views

Total abstract views: 0 *
Loading metrics...

* Views captured on Cambridge Core between <date>. This data will be updated every 24 hours.

Usage data cannot currently be displayed