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Published online by Cambridge University Press: 13 June 2014
Bipolar affective disorder has a usual age of onset in early adulthood. Adolescent onset occurs in some, prepubertal onset in a few. Early onset affective psychosis in two generations is rarer still and provides powerful evidence for a major genetic effect, especially where adoption removes confounding environmental stresses. We present just such a case in a mother and her daughter.
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