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Antipsychotic induced priapism in a man with an intellectual disability

Published online by Cambridge University Press:  13 June 2014

Rubina Anjum ,
Ashok Roy  and
Geoff Marston
Ashok Roy
Affiliation:
Brooklands, Coleshill Road, Marston Green, Birmingham, B37 7HL, England
Geoff Marston
Affiliation:
Riverhouse, Gulson Road Hospital, Gulson Road, Coventry, CV1 2HR, England
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Abstract

Priapism is a rare urological emergency, which can be associated with the use of psychotropic medication. The authors were able to find only one brief report of this condition in people with an intellectual disability. A case is reported in a man with moderate intellectual disability, who was receiving antipsychotic medication to manage extreme challenging behaviour. We discuss the condition and its implications for pharmacological treatments of behavioural disturbance in susceptible individuals.

Keywords

PriapismAntipsychoticsIntellectual disability
Type
Case Reports
Information
Irish Journal of Psychological Medicine , Volume 18 , Issue 3 , September 2001 , pp. 106 - 107
Copyright
Copyright © Cambridge University Press 2001

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References

1.Wing, L. severely retarded children in a London area; prevalence and provision of services. Psychol Med 1971; 1: 405–15.CrossRefGoogle Scholar
2.Kushlik, A, Cox, GR. The epidemiology of mental handicap. Develop Medi Child Neurol 1973; 15: 748–59.CrossRefGoogle Scholar
3.Holt, G. Mental health in mental retardation. Recent advances and practices. Bouras, N (Ed) Cambridge University Press 1994; 126–32.Google Scholar
4.Manchester, D. Neuroleptics; learning disabilities and the community; some history and mystery. BMJ 1993; 307: 184–7.CrossRefGoogle ScholarPubMed
5.Chadsey-Rusch, J, Sprange, RL. Maladaptive behaviours associated with neuroleptic drug maintenance. AJMR 1989; 93(6): 607–17.Google ScholarPubMed
6.Gualtiere, C. The differential diagnosis of self-injurious behaviour in mentally retarded people. Psychopharmacol Bull 1989; 25(3): 358–63.Google Scholar
7.Patel, AG, Mukherji, K, Lee, A. Priapism associated with psychotropic drugs. Br J Hosp Med 1996; 55(6): 315–19.Google ScholarPubMed
8.Psychotropic Drugs Directory (2000) Priapism 2.5.4 P143 - 144Google Scholar
9.Behar, Ziegler. Clozapine induced priapism. Am J Psychiat 1992; 149: 272–3.Google Scholar
10.Lue, TFet al.Priapism: a refined approach to diagnosis and treatment. J Urology 1986; 136; 104–8CrossRefGoogle ScholarPubMed
11 Hinman, F Jnr.Priapism: reasons for failure of therapy. J Urology 1960; 83; 420–8CrossRefGoogle ScholarPubMed
12 Kogeorgos, J, de Alwis, C. Priapism and psychotropic medication. Br J Psychiat 1986; 149; 241CrossRefGoogle ScholarPubMed
13 Abber, JCet al.Priapism induced by chlorpromazine and trazodone. Mechanisms of action. J Urology 1987; 137; 1039–42.CrossRefGoogle Scholar
14 Chen, EYH, Lee, AS. Neuroleptic induced priapism, hepatotoxicity and subsequent impotence in a patient with depressive psychosis. Br J Psychiat 1990; 157; 759–62.CrossRefGoogle Scholar
15.Griffith, SR, Zil, JS. Priapism in a patient receiving antipsychotic therapy. Psychosomatics 1984; 25: 629–31.CrossRefGoogle Scholar
16.Balon, R, Berchou, R, Han, H. Priapism associated with thiothixene, chlorpromazine and thioridazine. J Clin Psychiat 1987; 48: 216Google ScholarPubMed
17.Greenberg, WM, Lee, KK. Priapism treated with benztropine. Am J Psychiat 1987; 144; 384–5Google ScholarPubMed
18.Greenberg, WM, Lee, KK. Beta blockers for the treatment of priapism associated with use of neuroleptics. Am J Psychiat 1988; 145; 1480Google ScholarPubMed
19.Gold, DD, Justin, JD. ‘Bicycle Kickstand’ Phenomenon: prolonged erections associated with antipsychotic agents. Southern Med J 1988; 81,6: 792–794.CrossRefGoogle ScholarPubMed