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Verbal fluency as a screening tool for mild cognitive impairment

  • Michelle McDonnell (a1), Lauren Dill (a2), Stella Panos (a3) (a4), Stacy Amano (a5), Warren Brown (a5), Shadee Giurgius (a6), Gary Small (a3) and Karen Miller (a3)...

Abstract

Objectives:

The goal of this study was to evaluate the ability of semantic (animal naming) and phonemic (FAS) fluency in their ability to discriminate between normal aging, amnestic-Mild Cognitive Impairment (a-MCI), and Alzheimer’s disease (AD).

Design:

We used binary logistic regressions, multinomial regressions, and discriminant analysis to evaluate the predictive value of semantic and phonemic fluency in regards to specific diagnostic classifications.

Setting:

Outpatient geriatric neuropsychology clinic.

Participants:

232 participants (normal aging = 99, a-MCI = 90, AD = 43; mean age = 65.75 years).

Measurements:

Mini-mental State Examination (MMSE), Controlled Oral Word Association Test

Results:

Results indicate that semantic and phonemic fluency were significant predictors of diagnostic classification, and semantic fluency explained a greater amount of the discriminant ability of the model.

Conclusions:

These results suggest that verbal fluency, particularly semantic fluency, may be an accurate and efficient tool in screening for early dementia in time-limited medical settings.

Copyright

Corresponding author

*Correspondence should be addressed to: Karen Miller, UCLA Longevity Center, 10945 Le Conte Avenue, Suite 3119, Los Angeles, CA 90095-6980, USA. Phone: 310-267-2663; Fax: 310-794-0681. Email: KMiller@mednet.ucla.edu.

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Keywords

Verbal fluency as a screening tool for mild cognitive impairment

  • Michelle McDonnell (a1), Lauren Dill (a2), Stella Panos (a3) (a4), Stacy Amano (a5), Warren Brown (a5), Shadee Giurgius (a6), Gary Small (a3) and Karen Miller (a3)...

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