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Carotid Endarterectomy for Asymptomatic Patients: Assessing Results of a Quantitative Synthesis

Published online by Cambridge University Press:  10 March 2009

John C. Langenbrunner ,
Paul M. Wortman ,
William H. Yeaton  and
James J. Holloway
John C. Langenbrunner
Affiliation:
Office of Management and Budget, Washington, DC
Paul M. Wortman
Affiliation:
State University of New York, Stony Brook
William H. Yeaton
Affiliation:
University of Michigan School of Public Health
James J. Holloway
Affiliation:
Lakeside Medical Center, Chicago
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Abstract

Carotid endarterectomy (CE) surgery for asymptomatic patients remains controversial despite hundreds of published studies and recent randomized trials. Safety and efficacy are assessed using a quantitative synthesis method derived from meta-analysis and a “critical multiplist” inference approach. In addition, multivariate analyses reveal that use of a surgical shunt could further improve CE outcomes. Methods are examined for both their “confirmatory” and “exploratory” value.

Type
General Essays
Information
International Journal of Technology Assessment in Health Care , Volume 9 , Issue 2 , Spring 1993 , pp. 286 - 303
Copyright
Copyright © Cambridge University Press 1993

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