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CHALLENGES FACED IN TRANSFERRING ECONOMIC EVALUATIONS TO MIDDLE INCOME COUNTRIES

Published online by Cambridge University Press:  01 February 2016

Michael Drummond
Affiliation:
University of York mike.drummond@york.ac.uk
Federico Augustovski
Affiliation:
Institute for Clinical Effectiveness and Health Policy, University of Buenos Aires
Zoltán Kaló
Affiliation:
Syreon Research Institute, Department of Health Policy and Health Economics, Eötvös Loránd University, Budapest
Bong-Min Yang
Affiliation:
School of Public Health, Seoul National University
Andres Pichon-Riviere
Affiliation:
Institute for Clinical Effectiveness and Health Policy, University of Buenos Aires
Eun-Young Bae
Affiliation:
College of Pharmacy, Gyeongsang National University
Sachin Kamal-Bahl
Affiliation:
HTA Strategy, Global Market Access, Merck and Co.
Corresponding
E-mail address:

Abstract

Background: Decision makers in middle-income countries are using economic evaluations (EEs) in pricing and reimbursement decisions for pharmaceuticals. However, whilst many of these jurisdictions have local submission guidelines and local expertise, the studies themselves often use economic models developed elsewhere and elements of data from countries other than the jurisdiction concerned. The objectives of this study were to describe the current situation and to assess the challenges faced by decision makers in transferring data and analyses from other jurisdictions.

Methods: Experienced health service researchers in each region conducted an interview survey of representatives of decision making bodies from jurisdictions in Asia, Central and Eastern Europe, and Latin America that had at least 1 year's experience of using EEs.

Results: Representatives of the relevant organizations in twelve countries were interviewed. All twelve jurisdictions had developed official guidelines for the conduct of EEs. All but one of the organizations evaluated studies submitted to them, but 9 also conducted studies and 7 commissioned them. Nine of the organizations stated that, in evaluating EEs submitted to them, they had consulted a study performed in a different jurisdiction. Data on relevant treatment effect was generally considered more transferable than those on prices/unit costs. Views on the transferability of epidemiological data, data on resource use and health state preference values were more mixed. Eight of the respondents stated that analyses submitted to them had used models developed in other jurisdictions. Four of the organizations had a policy requiring models to be adapted to reflect local circumstances. The main obstacles to transferring EEs were the different patterns of care or wealth of the developed countries from which most economic evaluations originate.

Conclusions: In middle-income countries it is commonplace to deal with the issue of transferring analyses or data from other jurisdictions. Decision makers in these countries face several challenges, mainly due to differences in current standard of care, practice patterns, or gross domestic product between the developed countries where the majority of the studies are conducted and their own jurisdiction

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Policies
Copyright
Copyright © Cambridge University Press 2016 

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References

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Drummond supplementary material S1

TRANSFERABILITY OF HTA QUESTIONNAIRE V2

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CHALLENGES FACED IN TRANSFERRING ECONOMIC EVALUATIONS TO MIDDLE INCOME COUNTRIES
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