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Variability of surgical prophylaxis in penicillin-allergic children

  • David F. Butler (a1), Brian R. Lee (a1), Sarah Suppes (a2), Tracy Sandritter (a2), Jason G. Newland (a3), Lory Harte (a2) and Jennifer L. Goldman (a1)...

Abstract

We retrospectively evaluated the effect of penicillin adverse drug reaction (ADR) labeling on surgical antibiotic prophylaxis. Cefazolin was administered in 86% of penicillin ADR-negative (−) and 28% penicillin ADR-positive (+) cases. Broad-spectrum antibiotic use was more common in ADR(+) cases and was more commonly associated with perioperative adverse drug events.

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Corresponding author

Authors for correspondence: David F. Butler, MD, Division of Pediatric Critical Care Medicine, Department of Pediatrics, Seattle Children’s Hospital, University of Washington School of Medicine, FA.2.112, 4800 Sand Point Way NE, Seattle WA 98105. E-mail: david.butler@seattlechildrens.org. Also, Jennifer Goldman MD, MS Divisions of Pediatric Infectious Diseases & Clinical Pharmacology, Department of Pediatrics, Children’s Mercy Hospital, 2401 Gillham Rd, Kansas City, MO 64108. E-mail: jlgoldman@cmh.edu

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Present affiliation: Division of Pediatric Critical Care, University of Washington, Seattle Children’s Hospital, Seattle, Washington.

Cite this article: Butler DF et al. (2018). Variability of surgical prophylaxis in penicillin-allergic children. Infection Control & Hospital Epidemiology 2018, 39, 1480–1483. doi: 10.1017/ice.2018.244

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References

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1. Kerr, JR. Penicillin allergy: a study of incidence as reported by patients. Brit J Clin Pract 1994;48:57.
2. Attia, MS, Stringer, MD, McClean, P, Prasad, KR. The reduced left lateral segment in pediatric liver transplantation: an alternative to the monosegment graft. Pediatr Transplant 2008;12:696700.
3. MacLaughlin, EJ, Saseen, JJ, Malone, DC. Costs of beta-lactam allergies: selection and costs of antibiotics for patients with a reported beta-lactam allergy. Arch Fam Med 2000;9:722726.
4. Alsultan, A, Peloquin, CA. Therapeutic drug monitoring in the treatment of tuberculosis: an update. Drugs 2014;74:839854.
5. Bratzler, DW, Dellinger, EP, Olsen, KM, et al. Clinical practice guidelines for antimicrobial prophylaxis in surgery. Am J Health Syst Pharm 2013;70:195283.
6. Sandora, TJ, Fung, M, Melvin, P, Graham, DA, Rangel, SJ. National variability and appropriateness of surgical antibiotic prophylaxis in US children’s hospitals. JAMA Pediatr 2016;170:570576.
7. National Expert Panel of the ICD-9-CM Adverse Event Classification, Utah/Missouri Patient Safety Consortium. The ICD-9-CM adverse event classification. Utah Department of Health website. health.utah.gov/psi/icd9.htm. Accessed June 25, 2018.
8. Goldman, JL, Sandritter, TL, Sullins, A, Leeder, JS, Lowry, JA. Pediatric pharmacovigilance: enhancing adverse drug reaction reporting in a tertiary care children’s hospital. Ther Innov Regulat Sci 2013;47:566571.
9. Beltran, RJ, Kako, H, Chovanec, T, Ramesh, A, Bissonnette, B, Tobias, JD. Penicillin allergy and surgical prophylaxis: cephalosporin cross-reactivity risk in a pediatric tertiary care center. J Pediatr Surg 2015;50:856859.
10. Albertson, TE, Chenoweth, JA, Colby, DK, Sutter, ME. The changing drug culture: use and misuse of appearance- and performance-enhancing drugs. FP Essent 2016;441:3043.
11. Hougland, P, Nebeker, J, Pickard, S, et al. Using ICD-9-CM codes in hospital claims data to detect adverse events in patient safety surveillance. In: Henriksen K, Battles JB, Keyes MA, et al., editors. Advances in Patient Safety: New Directions and Alternative Approaches, Vol. 1: Assessment. Rockville, MD: Agency for Healthcare Research and Quality; 2008.
12. Hougland, P, Xu, W, Pickard, S, Masheter, C, Williams, SD. Performance of International Classification of Diseases, 9th Revision, Clinical Modification codes as an adverse drug event surveillance system. Med Care 2006;44:629636.
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Infection Control & Hospital Epidemiology
  • ISSN: 0899-823X
  • EISSN: 1559-6834
  • URL: /core/journals/infection-control-and-hospital-epidemiology
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