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Vancomycin-Resistant Enterococcus faecium in Hospitalized Children

Published online by Cambridge University Press:  21 June 2016

Lorry G. Rubin ,
Victor Tucci ,
Emilia Cercenado ,
George Eliopoulos  and
Henry D. Isenberg
Lorry G. Rubin*
Affiliation:
Division of Pediatric Infectious Diseases, Schneider Children's Hospital of Long Island Jewish Medical Center, New Hyde Park, New York
Victor Tucci
Affiliation:
Division of Microbiology, Long Island Jewish Medical Center, Long Island Campus for Albert Einstein College of Medicine, New Hyde Park, New York
Emilia Cercenado
Affiliation:
Department of Medicine, New England Deaconess Hospital, Boston, Massachusetts and Harvard Medical School, Boston, Massachusetts
George Eliopoulos
Affiliation:
Department of Medicine, New England Deaconess Hospital, Boston, Massachusetts and Harvard Medical School, Boston, Massachusetts
Henry D. Isenberg
Affiliation:
Division of Microbiology, Long Island Jewish Medical Center, Long Island Campus for Albert Einstein College of Medicine, New Hyde Park, New York
*
Division of Pediatric Infectious Diseases, Schneider Children's Hospital, of Long Island Jewish Medical Center, New Hyde Park, NY 11042
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Abstract

Objectve:

Determine the epidemiology and risk factors for colonization with vancomycin-resistant Enterococcus faecium.

Design:

Survey; case-control study.

Setting:

Children's hospital.

Patients:

Pediatric oncology patients.

Intervention:

Contact isolation, restriction of vancomycin prescribing.

Results:

There was a high prevalence of colonization with vancomycin-resistant enterococci among pediatric oncology patients. The length of hospitalization and the administration of vancomycin and other intravenous antibiotics was associated with colonization. Prevention of colonization was associated with restriction of vancomycin use and contact isolation.

Conclusions:

Vancomycin use may predispose to colonization with vancomycin-resistant E faecium. Vancomycin-resistant E faecium may be nosocomially spread. Contact isolation and restriction of vancomycin use may prevent spread of vancomycin-resistant E faecium.

Type
Original Articles
Information
Infection Control & Hospital Epidemiology , Volume 13 , Issue 12 , December 1992 , pp. 700 - 705
Copyright
Copyright © The Society for Healthcare Epidemiology of America 1992

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