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Unintended consequences of a reflex urine culture order set on appropriate antibiotic use

  • Corinne N. Klein (a1), Miriam R. Elman (a2), John M. Townes (a3), James S. Lewis (a3) (a4) (a5) and Jessina C. McGregor (a2) (a5)...

Abstract

We evaluated the impact of reflex urine culture screen results on antibiotic initiation. More patients with positive urine screen but negative culture received antibiotics than those with a negative screen (30.5 vs 7.1%). Urine screen results may inappropriately influence antibiotic initiation in patients with a low likelihood of infection.

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Author for correspondence: Jessina C. McGregor, E-mail: mcgregoj@ohsu.edu

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PREVIOUS PRESENTATION. Preliminary data from this research were previously presented at IDWeek 2015 on October 10, 2015, in San Diego, California.

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1.Grein, JD, Kahn, KL, Eells, SJ, et al.Treatment for positive urine cultures in hospitalized adults: a survey of prevalence and risk factors in 3 medical centers. Infect Control Hosp Epidemiol 2016;37:319326.
2.Daniel, M, Keller, S, Mozafarihashjin, M, Pahwa, A, Soong, C. An implementation guide to reducing overtreatment of asymptomatic bacteriuria. JAMA Intern Med 2018;178:271276.
3.Garcia, R, Spitzer, ED. Promoting appropriate urine culture management to improve health care outcomes and the accuracy of catheter-associated urinary tract infections. Am J Infect Control 2017;45:11431153.10.1016/j.ajic.2017.03.006
4.Sarg, M, Waldrop, GE, Beier, MA, et al.Impact of changes in urine culture ordering practice on antimicrobial utilization in intensive care units at an academic medical center. Infect Control Hosp Epidemiol 2016;37:448454.

Unintended consequences of a reflex urine culture order set on appropriate antibiotic use

  • Corinne N. Klein (a1), Miriam R. Elman (a2), John M. Townes (a3), James S. Lewis (a3) (a4) (a5) and Jessina C. McGregor (a2) (a5)...

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