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Surveillance Cultures for Detection of Methicillin-Resistant Staphylococcus aureus: Diagnostic Yield of Anatomic Sites and Comparison of Provider- and Patient-Collected Samples

  • Ebbing Lautenbach (a1) (a2) (a3) (a4), Irving Nachamkin (a5), Baofeng Hu (a5) (a3), Neil O. Fishman (a1) (a4), Pam Tolomeo (a3), Priya Prasad (a6), Warren B. Bilker (a2) (a3) (a4) and Theoklis E. Zaoutis (a2) (a3) (a4) (a6)...


We studied provider- and patient-collected samples from multiple anatomic sites to determine the yield for detection of methicillin-resistant Staphylococcus aureus (MRSA). Sampling of multiple sites was required to achieve a sensitivity of more than 90% for MRSA colonization. Groin and perineum samples yielded positive results significantly more often for community-onset MRSA than for hospital-onset MRSA. Agreement rates between provider- and patient-collected swab specimens were excellent.


Corresponding author

University of Pennsylvania School of Medicine, Center for Clinical Epidemiology and Biostatistics, 825 Blockley Hall, 423 Guardian Dr., Philadelphia, PA 19104-6021 (


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