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Smallpox Vaccine: “Non-Take” Responses in Previously Vaccinated Adults

Published online by Cambridge University Press:  02 January 2015

Georgia Thomas*
Affiliation:
Department of Infectious Diseases, Infection Control and Employee Health, The University of Texas M. D. Anderson Cancer Center, Houston, Texas
Elizabeth Frenzel
Affiliation:
Department of Infectious Diseases, Infection Control and Employee Health, The University of Texas M. D. Anderson Cancer Center, Houston, Texas
Hend Hanna
Affiliation:
Department of Infectious Diseases, Infection Control and Employee Health, The University of Texas M. D. Anderson Cancer Center, Houston, Texas
*
Department of Infectious Diseases, Infection Control and Employee Health (Unit 631), The University of Texas M. D. Anderson Cancer Center, 1515 Holcombe Blvd., Houston, TX 77030

Abstract

This small, retrospective study of laboratory workers who received smallpox vaccine showed a strong correlation between “non-take” reactions and the presence of prior vaccination scars. Although we cannot exclude technique and vaccine potency as causes, the association we observed may indicate that these workers are displaying residual immunity to smallpox.

Type
Concise Communications
Copyright
Copyright © The Society for Healthcare Epidemiology of America 2004

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