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Role of Coinfecting Strains in Recurrent Clostridium difficile Infection

  • Janet Sun (a1), Tracy Mc Millen (a1) (a2), N. Esther Babady (a2) and Mini Kamboj (a1) (a3) (a4)


The contribution of mixed infection in recurrent Clostridium difficile infection (CDI) episodes is not known. Among paired isolates from 52 patients, mixed infection due to >1 toxigenic strain of C. difficile was identified in 8% of first episodes. Among recurrences, relapse from 1 or both co-infecting strains was uncommon; it was detected in a single case each.

Infect Control Hosp Epidemiol 2016;1481–1484


Corresponding author

Address correspondence to Mini Kamboj, 1275 York Avenue, New York, NY 10065 (


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